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Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene.
Thomas KR, Capecchi MR. Thomas KR, et al. Among authors: capecchi mr. Nature. 1986 Nov 6-12;324(6092):34-8. doi: 10.1038/324034a0. Nature. 1986. PMID: 3785372
Gene targeting. How efficient can you get?
Capecchi M. Capecchi M. Nature. 1990 Nov 8;348(6297):109. doi: 10.1038/348109a0. Nature. 1990. PMID: 2234072 No abstract available.
Gene targeting: tapping the cellular telephone.
Capecchi M. Capecchi M. Nature. 1990 Mar 8;344(6262):105. doi: 10.1038/344105a0. Nature. 1990. PMID: 2308628 No abstract available.
Establishment of mammalian cell lines containing multiple nonsense mutations and functional suppressor tRNA genes.
Hudziak RM, Laski FA, RajBhandary UL, Sharp PA, Capecchi MR. Hudziak RM, et al. Among authors: capecchi mr. Cell. 1982 Nov;31(1):137-46. doi: 10.1016/0092-8674(82)90413-5. Cell. 1982. PMID: 6760983
Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells.
Laski FA, Belagaje R, Hudziak RM, Capecchi MR, Norton GP, Palese P, RajBhandary UL, Sharp PA. Laski FA, et al. Among authors: capecchi mr. EMBO J. 1984 Nov;3(11):2445-52. EMBO J. 1984. PMID: 6096120 Free PMC article.
Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules.
Folger KR, Wong EA, Wahl G, Capecchi MR. Folger KR, et al. Among authors: capecchi mr. Mol Cell Biol. 1982 Nov;2(11):1372-87. doi: 10.1128/mcb.2.11.1372. Mol Cell Biol. 1982. PMID: 6298598 Free PMC article.
Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase.
Wong EA, Capecchi MR. Wong EA, et al. Among authors: capecchi mr. Mol Cell Biol. 1987 Jun;7(6):2294-5. doi: 10.1128/mcb.7.6.2294. Mol Cell Biol. 1987. PMID: 3600663 Free PMC article.
High frequency targeting of genes to specific sites in the mammalian genome.
Thomas KR, Folger KR, Capecchi MR. Thomas KR, et al. Among authors: capecchi mr. Cell. 1986 Feb 14;44(3):419-28. doi: 10.1016/0092-8674(86)90463-0. Cell. 1986. PMID: 3002636
Maintenance of functional equivalence during paralogous Hox gene evolution.
Greer JM, Puetz J, Thomas KR, Capecchi MR. Greer JM, et al. Among authors: capecchi mr. Nature. 2000 Feb 10;403(6770):661-5. doi: 10.1038/35001077. Nature. 2000. PMID: 10688203
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions.
Condie BG, Capecchi MR. Condie BG, et al. Among authors: capecchi mr. Nature. 1994 Jul 28;370(6487):304-7. doi: 10.1038/370304a0. Nature. 1994. PMID: 7913519
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