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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 1
1948 2
1950 3
1951 1
1952 1
1953 1
1954 1
1955 2
1956 2
1957 6
1958 1
1959 2
1960 3
1961 3
1962 2
1963 2
1964 4
1965 9
1966 2
1967 7
1968 3
1969 9
1970 6
1971 4
1972 2
1973 1
1974 3
1975 8
1976 11
1977 14
1978 8
1979 19
1980 41
1981 53
1982 84
1983 91
1984 125
1985 117
1986 146
1987 180
1988 188
1989 228
1990 298
1991 336
1992 335
1993 378
1994 336
1995 367
1996 358
1997 396
1998 379
1999 406
2000 411
2001 460
2002 437
2003 494
2004 507
2005 562
2006 549
2007 582
2008 616
2009 589
2010 602
2011 603
2012 591
2013 604
2014 617
2015 566
2016 583
2017 590
2018 566
2019 547
2020 612
2021 601
2022 572
2023 515
2024 197

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17,001 results

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Page 1
Selective modification of ascending spinal outputs in acute and neuropathic pain states.
Yarmolinsky DA, Zeng X, MacKinnon-Booth N, Greene C, Kim C, Woolf CJ. Yarmolinsky DA, et al. bioRxiv [Preprint]. 2024 Apr 9:2024.04.08.588581. doi: 10.1101/2024.04.08.588581. bioRxiv. 2024. PMID: 38645252 Free PMC article. Preprint.
In healthy conditions, we identify stable, narrowly tuned outputs selective for cooling or warming, and a neuronal ensemble activated by intense/noxious thermal and mechanical stimuli. Induction of an acute peripheral sensitization with capsaicin selectively and transientl …
In healthy conditions, we identify stable, narrowly tuned outputs selective for cooling or warming, and a neuronal ensemble activated by int …
Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin.
Salib AN, Crane MJ, Lee SH, Wainger BJ, Jamieson AM, Lipscombe D. Salib AN, et al. Sci Rep. 2024 Apr 20;14(1):9051. doi: 10.1038/s41598-024-59424-6. Sci Rep. 2024. PMID: 38643253 Free PMC article.
Of 20 cytokines screened, only IL-1alpha was consistently detected in hind paw interstitial fluid in response to intradermal capsaicin and, similar to behavioral sensitivity to heat, IL-1alpha levels were also dependent on peripheral Ca(V)2.2 channel activity. Neutralizing …
Of 20 cytokines screened, only IL-1alpha was consistently detected in hind paw interstitial fluid in response to intradermal capsaicin …
Neuropathic pain: Evidence based recommendations.
Moisset X. Moisset X. Presse Med. 2024 Apr 17:104232. doi: 10.1016/j.lpm.2024.104232. Online ahead of print. Presse Med. 2024. PMID: 38641202
Additionally, tramadol, combination therapies, and psychotherapy as adjuncts are proposed second line; high-concentration capsaicin patches, and botulinum toxin A are proposed specifically for focal peripheral neuropathic pain. ...
Additionally, tramadol, combination therapies, and psychotherapy as adjuncts are proposed second line; high-concentration capsaicin p …
A highly-sensitive electrochemical sensor based on Ni nanoparticles modified carbon nanotubes/sulfonated reduced graphene oxide for the detection of capsaicinoids in leisure sauced meat products.
Chen X, Xie T, Wang Z, Gu Q. Chen X, et al. Food Chem. 2024 Apr 4;450:139257. doi: 10.1016/j.foodchem.2024.139257. Online ahead of print. Food Chem. 2024. PMID: 38640526
In this work, an electrochemical sensor based on nickel nanoparticles modified carbon nanotubes (Ni-CNTs) and sulfonated reduced graphene oxide (S-rGO) was developed for the rapid detection of capsaicinoids content in leisure sauced meat products. The linear ranges of capsaici …
In this work, an electrochemical sensor based on nickel nanoparticles modified carbon nanotubes (Ni-CNTs) and sulfonated reduced graphene ox …
WITHANICANDRIN ISOLATED FROM Datura Ferox PROMOTES ANTINOCICEPTION BY MODULATING THE ASICS AND TRPS CHANNELS AND ANTI-INFLAMMATION IN ADULT ZEBRAFISH.
Maciel JB, Liberato HR, Wlisses da Silva A, Vieira da Silva JP, Pinto FDCL, de Lima Rebouças E, Henrique da Silva FS, Ferreira MKA, Marinho MM, Marinho ES, Pessoa ODL, de Barros Silva PG, de-Souza ANC, Florindo Guedes MI, de Castro Gomes AF, de Menezes JESA, Dos Santos HS. Maciel JB, et al. Chem Biodivers. 2024 Apr 19:e202400538. doi: 10.1002/cbdv.202400538. Online ahead of print. Chem Biodivers. 2024. PMID: 38639566
As a result, withanicandrin reduced nociceptive behavior by capsaicin at a dose of 40 mg/kg and by acid saline at doses of 4 and 40 mg/kg, through neuromodulation of TRPV1 channels and ASICs, identified through blocking the antinociceptive effect of withanicandrin by the a …
As a result, withanicandrin reduced nociceptive behavior by capsaicin at a dose of 40 mg/kg and by acid saline at doses of 4 and 40 m …
Ecology, genetic diversity, and population structure among commercial varieties and local landraces of Capsicum spp. grown in northeastern states of India.
Verma VK, Pandey A, Thirugnanavel A, Rymbai H, Dutta N, Kumar A, Bhutia TL, Jha AK, Mishra VK. Verma VK, et al. Front Plant Sci. 2024 Apr 4;15:1379637. doi: 10.3389/fpls.2024.1379637. eCollection 2024. Front Plant Sci. 2024. PMID: 38638355 Free PMC article.
For quality traits, landraces king-chilli, dalle-chilli, and bird's eye chilli have shown 2.8, 2.0, and 1.4 times higher average capsaicin and 0.46, 0.25, and 0.22 times higher average oleoresin content over the hot pepper, respectively. ...
For quality traits, landraces king-chilli, dalle-chilli, and bird's eye chilli have shown 2.8, 2.0, and 1.4 times higher average capsaici …
Positive effect of deep diaphragmatic breathing training on gastroesophageal reflux-induced chronic cough: a clinical randomized controlled study.
Niu S, Zhang T, Li W, Wen S, Dong L, Wang S, Shi W, Shi C, Shen Y, Huang Q, Tan Y, Xu X, Yu L. Niu S, et al. Respir Res. 2024 Apr 18;25(1):169. doi: 10.1186/s12931-024-02783-5. Respir Res. 2024. PMID: 38637797 Free PMC article. Clinical Trial.
Both groups were evaluated by cough symptom scores, Hull airway reflux questionnaire (HARQ), gastroesophageal reflux diagnostic questionnaire (GerdQ), generalized anxiety disorder scale-7 (GAD-7), patient health questionnaire-9 (PHQ-9), Pittsburgh sleep quality index (PSQI), the …
Both groups were evaluated by cough symptom scores, Hull airway reflux questionnaire (HARQ), gastroesophageal reflux diagnostic questionnair …
CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland.
Ma L, Yang L, Wang X, Zhao L, Bai X, Qi X, Chen Q, Li Y, Zhou Q. Ma L, et al. Invest Ophthalmol Vis Sci. 2024 Apr 1;65(4):30. doi: 10.1167/iovs.65.4.30. Invest Ophthalmol Vis Sci. 2024. PMID: 38635244 Free PMC article.
METHODS: Mouse corneal denervation models were constructed through surgical axotomy, pharmacologic treatment with capsaicin or resiniferatoxin, and Trpv1-Cre/DTR mice with diphtheria toxin injection. The capsaicin-treated mice received subconjunctival injection of C …
METHODS: Mouse corneal denervation models were constructed through surgical axotomy, pharmacologic treatment with capsaicin or resini …
Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain.
Alexandre C, Miracca G, Holanda VD, Sharma A, Kourbanova K, Ferreira A, Bicca MA, Zeng X, Nassar VA, Lee S, Kaur S, Sarma SV, Sacré P, Scammell TE, Woolf CJ, Latremoliere A. Alexandre C, et al. Sci Transl Med. 2024 Apr 17;16(743):eadg3036. doi: 10.1126/scitranslmed.adg3036. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630850
Here, we performed a comprehensive electroencephalogram/electromyogram analysis of sleep in several mouse models of chronic pain: neuropathic (spared nerve injury and chronic constriction injury), inflammatory (Freund's complete adjuvant and carrageenan, plantar incision) and che …
Here, we performed a comprehensive electroencephalogram/electromyogram analysis of sleep in several mouse models of chronic pain: neuropathi …
Home screening of taste and oral trigeminal function: a feasibility study.
Green T, Mastinu M, Wolf A, Oleszkiewicz A, Aronis A, Hummel T, Pepino MY, Niv MY. Green T, et al. Eur Arch Otorhinolaryngol. 2024 Apr 17. doi: 10.1007/s00405-024-08654-5. Online ahead of print. Eur Arch Otorhinolaryngol. 2024. PMID: 38630275
Using paper strips impregnated with sweet, bitter, salty, or sour tastants, and with two trigeminal stimuli (capsaicin, tannins) in high and low concentrations, we assessed gustatory and trigeminal function in 74 participants (47 women) in the lab, where paper strips were …
Using paper strips impregnated with sweet, bitter, salty, or sour tastants, and with two trigeminal stimuli (capsaicin, tannins) in h …
17,001 results
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