Carazo A - Search Results

1

2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.

Smutny T, Nova A, Drechslerová M, Carazo A, Hyrsova L, Hrušková ZR, Kuneš J, Pour M, Špulák M, Pavek P. Smutny T, et al. Among authors: carazo a. J Med Chem. 2016 May 26;59(10):4601-10. doi: 10.1021/acs.jmedchem.5b01891. Epub 2016 May 12. J Med Chem. 2016. PMID: 27145071

2

The Antiplatelet Effect of 4-Methylcatechol in a Real Population Sample and Determination of the Mechanism of Action.

Hrubša M, Konečný L, Paclíková M, Parvin MS, Skořepa P, Musil F, Karlíčková J, Javorská L, Matoušová K, Krčmová LK, Carazo A, Šmahelová A, Blaha V, Mladěnka P. Hrubša M, et al. Among authors: carazo a. Nutrients. 2022 Nov 13;14(22):4798. doi: 10.3390/nu14224798. Nutrients. 2022. PMID: 36432485 Free PMC article.

3

The Impact of Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies with and without Apheresis on Platelet Aggregation in Familial Hypercholesterolemia.

Konečný L, Hrubša M, Karlíčková J, Carazo A, Javorská L, Matoušová K, Krčmová LK, Blaha V, Bláha M, Mladěnka P. Konečný L, et al. Among authors: carazo a. Cardiovasc Drugs Ther. 2023 May 2. doi: 10.1007/s10557-023-07455-y. Online ahead of print. Cardiovasc Drugs Ther. 2023. PMID: 37129685

4

The Effect of 4-Methylcatechol on Platelets in Familial Hypercholesterolemic Patients Treated with Lipid Apheresis and/or Proprotein Convertase Subtilisin Kexin 9 Monoclonal Antibodies.

Konečný L, Hrubša M, Karlíčková J, Carazo A, Javorská L, Matoušová K, Krčmová LK, Šmahelová A, Blaha V, Bláha M, Mladěnka P. Konečný L, et al. Among authors: carazo a. Nutrients. 2023 Apr 11;15(8):1842. doi: 10.3390/nu15081842. Nutrients. 2023. PMID: 37111061 Free PMC article.

5

The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.

Soukup T, Dosedel M, Pavek P, Nekvindova J, Barvik I, Bubancova I, Bradna P, Kubena AA, Carazo AF, Veleta T, Vlcek J. Soukup T, et al. Rheumatol Int. 2015 Jul;35(7):1149-61. doi: 10.1007/s00296-015-3219-z. Epub 2015 Jan 25. Rheumatol Int. 2015. PMID: 25618758

6

The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists.

Carazo A, Pávek P. Carazo A, et al. Sensors (Basel). 2015 Apr 21;15(4):9265-76. doi: 10.3390/s150409265. Sensors (Basel). 2015. PMID: 25905697 Free PMC article.

7

The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator.

Hyrsova L, Smutny T, Carazo A, Moravcik S, Mandikova J, Trejtnar F, Gerbal-Chaloin S, Pavek P. Hyrsova L, et al. Among authors: carazo a. Br J Pharmacol. 2016 May;173(10):1703-15. doi: 10.1111/bph.13472. Epub 2016 Apr 8. Br J Pharmacol. 2016. PMID: 26920453 Free PMC article.

8

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.

Carazo A, Hyrsova L, Dusek J, Chodounska H, Horvatova A, Berka K, Bazgier V, Gan-Schreier H, Chamulitrat W, Kudova E, Pavek P. Carazo A, et al. Toxicol Lett. 2017 Jan 4;265:86-96. doi: 10.1016/j.toxlet.2016.11.013. Epub 2016 Nov 18. Toxicol Lett. 2017. PMID: 27871908

9

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.

Karabanovich G, Němeček J, Valášková L, Carazo A, Konečná K, Stolaříková J, Hrabálek A, Pavliš O, Pávek P, Vávrová K, Roh J, Klimešová V. Karabanovich G, et al. Among authors: carazo a. Eur J Med Chem. 2017 Jan 27;126:369-383. doi: 10.1016/j.ejmech.2016.11.041. Epub 2016 Nov 21. Eur J Med Chem. 2017. PMID: 27907875

10

Correction to 2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.

Smutny T, Nova A, Drechslerová M, Carazo A, Hyrsova L, Hrušková ZR, Kuneš J, Pour M, Špulák M, Pavek P. Smutny T, et al. Among authors: carazo a. J Med Chem. 2016 Dec 22;59(24):11195. doi: 10.1021/acs.jmedchem.6b01729. Epub 2016 Dec 8. J Med Chem. 2016. PMID: 28002962 No abstract available.

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