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2009 2
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2016 1
2017 1
2021 0
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Elevated Glucose Oxidation, Reduced Insulin Secretion, and a Fatty Heart May Be Protective Adaptions in Ischemic CAD.
Hannukainen JC, Lautamäki R, Mari A, Pärkkä JP, Bucci M, Guzzardi MA, Kajander S, Tuokkola T, Knuuti J, Iozzo P. Hannukainen JC, et al. J Clin Endocrinol Metab. 2016 Jul;101(7):2701-10. doi: 10.1210/jc.2015-4091. Epub 2016 Apr 5. J Clin Endocrinol Metab. 2016. PMID: 27045985 Free PMC article.
We used magnetic resonance imaging/spectroscopy, positron emission and computerized tomography to characterize CAD, cardiac function, pericardial and abdominal adipose tissue, and myocardial, liver, and pancreatic triglyceri …
We used magnetic resonance imaging/spectroscopy, positron emission and computerized tomography to …
Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations.
Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schäfers M, Nicolay K, Faber C, Hermann S, Prompers JJ. Abdurrachim D, et al. Cardiovasc Res. 2017 Aug 1;113(10):1148-1160. doi: 10.1093/cvr/cvx100. Cardiovasc Res. 2017. PMID: 28549111
METHODS AND RESULTS: Transverse aortic constriction (TAC) was performed in non-diabetic (db/+) and diabetic (db/db) mice to induce pressure overload. Magnetic resonance imaging, 31P magnetic resonance spectroscopy (MRS), 1H MRS, and 18F-fluorode …
METHODS AND RESULTS: Transverse aortic constriction (TAC) was performed in non-diabetic (db/+) and diabetic (db/db) mice to induce pressure …
Metabolic toxicity of the heart: insights from molecular imaging.
Iozzo P. Iozzo P. Nutr Metab Cardiovasc Dis. 2010 Mar;20(3):147-56. doi: 10.1016/j.numecd.2009.08.011. Epub 2009 Dec 22. Nutr Metab Cardiovasc Dis. 2010. PMID: 20031381 Review.
There is convincing evidence that alterations in myocardial substrate use play an important role in the normal and diseased heart. In this review, insights gained by using quantitative molecular imaging by positron emission tomography and magnetic
There is convincing evidence that alterations in myocardial substrate use play an important role in the normal and diseased heart. In …
Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus.
van der Meer RW, Rijzewijk LJ, de Jong HW, Lamb HJ, Lubberink M, Romijn JA, Bax JJ, de Roos A, Kamp O, Paulus WJ, Heine RJ, Lammertsma AA, Smit JW, Diamant M. van der Meer RW, et al. Circulation. 2009 Apr 21;119(15):2069-77. doi: 10.1161/CIRCULATIONAHA.108.803916. Epub 2009 Apr 6. Circulation. 2009. PMID: 19349323 Clinical Trial.
Pioglitazone has been associated with improved cardiac outcome but also with an elevated risk of heart failure. We determined the effects of pioglitazone on myocardial function in relation to cardiac high-energy phosphate, glucose, and fatty acid
Pioglitazone has been associated with improved cardiac outcome but also with an elevated risk of heart failure. We determined …