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Extracellular vesicles from patients with Acute Coronary Syndrome impact on ischemia-reperfusion injury.
D'Ascenzo F, Femminò S, Ravera F, Angelini F, Caccioppo A, Franchin L, Grosso A, Comità S, Cavallari C, Penna C, De Ferrari GM, Camussi G, Pagliaro P, Brizzi MF. D'Ascenzo F, et al. Pharmacol Res. 2021 Aug;170:105715. doi: 10.1016/j.phrs.2021.105715. Epub 2021 Jun 7. Pharmacol Res. 2021. PMID: 34111564 Free article. Clinical Trial.
The relevance of extracellular vesicles (EV) as mediators of cardiac damage or recovery upon Ischemia Reperfusion Injury (IRI) and Remote Ischemic PreConditioning (RIPC) is controversial. ...Pre-treatment of the rat heart wi …
The relevance of extracellular vesicles (EV) as mediators of cardiac damage or recovery upon Ischemia Reperfusion Injur …
Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles.
Lassen TR, Just J, Hjortbak MV, Jespersen NR, Stenz KT, Gu T, Yan Y, Su J, Hansen J, Bæk R, Jørgensen MM, Nyengaard JR, Kristiansen SB, Drasbek KR, Kjems J, Bøtker HE. Lassen TR, et al. Basic Res Cardiol. 2021 Mar 10;116(1):16. doi: 10.1007/s00395-021-00856-w. Basic Res Cardiol. 2021. PMID: 33689033
We studied the cardioprotective role of extracellular vesicles (EV)s released into the circulation after RIC and EV accumulation in injured myocardium. ...Labelled EVs accumulated more intensely in the infarct area than in sham hearts. CONCLUSIO …
We studied the cardioprotective role of extracellular vesicles (EV)s released into the circulation after RIC and …
Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles.
Giricz Z, Varga ZV, Baranyai T, Sipos P, Pálóczi K, Kittel Á, Buzás EI, Ferdinandy P. Giricz Z, et al. J Mol Cell Cardiol. 2014 Mar;68:75-8. doi: 10.1016/j.yjmcc.2014.01.004. Epub 2014 Jan 16. J Mol Cell Cardiol. 2014. PMID: 24440457 Free article.
Remote ischemic preconditioning (RIPC) of the heart is exerted by brief ischemic insults affected on a remote organ or a remote area of the heart before a sustained cardiac ischemia. ...Therefore, here we investigated whethe …
Remote ischemic preconditioning (RIPC) of the heart is exerted by brief ischemic insults affected on a …
Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposure.
Abel F, Murke F, Gaida M, Garnier N, Ochsenfarth C, Theiss C, Thielmann M, Kleinbongard P, Giebel B, Peters J, Frey UH. Abel F, et al. PLoS One. 2020 Feb 14;15(2):e0228948. doi: 10.1371/journal.pone.0228948. eCollection 2020. PLoS One. 2020. PMID: 32059016 Free PMC article. Clinical Trial.
Remote ischemic preconditioning (RIPC) can evoke cardioprotection following ischemia/reperfusion and this may depend on the anesthetic used. We tested whether 1) extracellular vesicles (EVs) isolated from humans undergoing RIPC protect ca …
Remote ischemic preconditioning (RIPC) can evoke cardioprotection following ischemia/reperfusion and this may de …
Remote ischemic preconditioning fails to reduce infarct size in the Zucker fatty rat model of type-2 diabetes: role of defective humoral communication.
Wider J, Undyala VVR, Whittaker P, Woods J, Chen X, Przyklenk K. Wider J, et al. Basic Res Cardiol. 2018 Mar 9;113(3):16. doi: 10.1007/s00395-018-0674-1. Basic Res Cardiol. 2018. PMID: 29524006 Free PMC article.
Remote ischemic preconditioning (RIPC), the phenomenon whereby brief ischemic episodes in distant tissues or organs render the heart resistant to infarction, has been exhaustively demonstrated in preclinical models. ...To investigate this issue, …
Remote ischemic preconditioning (RIPC), the phenomenon whereby brief ischemic episodes in distant tissues or org …
Plasma exosomes induced by remote ischaemic preconditioning attenuate myocardial ischaemia/reperfusion injury by transferring miR-24.
Minghua W, Zhijian G, Chahua H, Qiang L, Minxuan X, Luqiao W, Weifang Z, Peng L, Biming Z, Lingling Y, Zhenzhen W, Jianqing X, Huihui B, Xiaozhong W, Xiaoshu C. Minghua W, et al. Cell Death Dis. 2018 Feb 23;9(3):320. doi: 10.1038/s41419-018-0274-x. Cell Death Dis. 2018. PMID: 29476052 Free PMC article.
Remote ischaemic preconditioning (RIPC) is well known to protect the myocardium against ischaemia/reperfusion injury (IRI). Exosomes are small extracellular vesicles that have become the key mediators of intercellular communication. ...
Remote ischaemic preconditioning (RIPC) is well known to protect the myocardium against ischaemia/reperfusion injury (I …
Exosomal HSP90 induced by remote ischemic preconditioning alleviates myocardial ischemia/reperfusion injury by inhibiting complement activation and inflammation.
Cheng XF, He ST, Zhong GQ, Meng JJ, Wang M, Bi Q, Tu RH. Cheng XF, et al. BMC Cardiovasc Disord. 2023 Feb 1;23(1):58. doi: 10.1186/s12872-023-03043-y. BMC Cardiovasc Disord. 2023. PMID: 36726083 Free PMC article.
BACKGROUND/AIMS: The activation of the complement system and subsequent inflammatory responses are important features of myocardial ischemia/reperfusion (I/R) injury. Exosomes are nanoscale extracellular vesicles that play a significant role in remote isch …
BACKGROUND/AIMS: The activation of the complement system and subsequent inflammatory responses are important features of myocardial ischemia …