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Beyond the hormone: insulin as an autoimmune target in type 1 diabetes.
Brezar V, Carel JC, Boitard C, Mallone R. Brezar V, et al. Among authors: carel jc. Endocr Rev. 2011 Oct;32(5):623-69. doi: 10.1210/er.2011-0010. Epub 2011 Jun 23. Endocr Rev. 2011. PMID: 21700723 Review.
Can growth hormone treatment improve growth in children with severe growth failure due to anorexia nervosa? A preliminary pilot study.
Léger J, Fjellestad-Paulsen A, Bargiacchi A, Doyen C, Ecosse E, Carel JC, Le Heuzey MF. Léger J, et al. Among authors: carel jc. Endocr Connect. 2017 Nov;6(8):839-846. doi: 10.1530/EC-17-0200. Epub 2017 Oct 16. Endocr Connect. 2017. PMID: 29038330 Free PMC article.
Expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice.
Faideau B, Briand JP, Lotton C, Tardivel I, Halbout P, Jami J, Elliott JF, Krief P, Muller S, Boitard C, Carel JC. Faideau B, et al. Among authors: carel jc. J Immunol. 2004 Jan 1;172(1):25-33. doi: 10.4049/jimmunol.172.1.25. J Immunol. 2004. PMID: 14688305
Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice.
Thébault-Baumont K, Dubois-Laforgue D, Krief P, Briand JP, Halbout P, Vallon-Geoffroy K, Morin J, Laloux V, Lehuen A, Carel JC, Jami J, Muller S, Boitard C. Thébault-Baumont K, et al. Among authors: carel jc. J Clin Invest. 2003 Mar;111(6):851-7. doi: 10.1172/JCI16584. J Clin Invest. 2003. PMID: 12639991 Free PMC article.
Tolerance to proinsulin-2 is due to radioresistant thymic cells.
Faideau B, Lotton C, Lucas B, Tardivel I, Elliott JF, Boitard C, Carel JC. Faideau B, et al. Among authors: carel jc. J Immunol. 2006 Jul 1;177(1):53-60. doi: 10.4049/jimmunol.177.1.53. J Immunol. 2006. PMID: 16785498
Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients.
Toma A, Haddouk S, Briand JP, Camoin L, Gahery H, Connan F, Dubois-Laforgue D, Caillat-Zucman S, Guillet JG, Carel JC, Muller S, Choppin J, Boitard C. Toma A, et al. Among authors: carel jc. Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10581-6. doi: 10.1073/pnas.0504230102. Epub 2005 Jul 19. Proc Natl Acad Sci U S A. 2005. PMID: 16030147 Free PMC article.
HLA-B7-restricted islet epitopes are differentially recognized in type 1 diabetic children and adults and form weak peptide-HLA complexes.
Scotto M, Afonso G, Østerbye T, Larger E, Luce S, Raverdy C, Novelli G, Bruno G, Gonfroy-Leymarie C, Launay O, Lemonnier FA, Buus S, Carel JC, Boitard C, Mallone R. Scotto M, et al. Among authors: carel jc. Diabetes. 2012 Oct;61(10):2546-55. doi: 10.2337/db12-0136. Diabetes. 2012. PMID: 22997432 Free PMC article.
Safety of recombinant human growth hormone.
Carel JC, Butler G. Carel JC, et al. Endocr Dev. 2010;18:40-54. doi: 10.1159/000316126. Epub 2010 Jun 3. Endocr Dev. 2010. PMID: 20523016 Review.
Role of beta-cells in type 1 diabetes pathogenesis.
Faideau B, Larger E, Lepault F, Carel JC, Boitard C. Faideau B, et al. Among authors: carel jc. Diabetes. 2005 Dec;54 Suppl 2:S87-96. doi: 10.2337/diabetes.54.suppl_2.s87. Diabetes. 2005. PMID: 16306346 Review.
Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes.
Toma A, Laïka T, Haddouk S, Luce S, Briand JP, Camoin L, Connan F, Lambert M, Caillat-Zucman S, Carel JC, Muller S, Choppin J, Lemonnier F, Boitard C. Toma A, et al. Among authors: carel jc. Diabetes. 2009 Feb;58(2):394-402. doi: 10.2337/db08-0599. Epub 2008 Nov 14. Diabetes. 2009. PMID: 19011169 Free PMC article.
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