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Did you mean crago hr (1 results)?
Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise.
Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Whitham M, et al. Cell Metab. 2018 Jan 9;27(1):237-251.e4. doi: 10.1016/j.cmet.2017.12.001. Cell Metab. 2018. PMID: 29320704 Free article. Clinical Trial.
Recognizing that many circulating proteins are packaged in extracellular vesicles (EVs), we employed quantitative proteomic techniques to characterize the exercise-induced secretion of EV-contained proteins. Following a 1-hr bout of cycling exercise in healthy humans, we o …
Recognizing that many circulating proteins are packaged in extracellular vesicles (EVs), we employed quantitative proteomic techniques to ch …
Extracellular Vesicles as Innovative Tool for Diagnosis, Regeneration and Protection against Neurological Damage.
Andjus P, Kosanović M, Milićević K, Gautam M, Vainio SJ, Jagečić D, Kozlova EN, Pivoriūnas A, Chachques JC, Sakaj M, Brunello G, Mitrecic D, Zavan B. Andjus P, et al. Int J Mol Sci. 2020 Sep 18;21(18):6859. doi: 10.3390/ijms21186859. Int J Mol Sci. 2020. PMID: 32962107 Free PMC article. Review.
According to the mode of biogenesis, size and composition, two broad categories of EVs have been described, exosomes and microvesicles. EVs have been shown to carry cargoes of signaling proteins, RNA species, DNA and lipids. Once released, their content is selectively take …
According to the mode of biogenesis, size and composition, two broad categories of EVs have been described, exosomes and microvesicles. EVs …
Stimulus-dependent modifications in astrocyte-derived extracellular vesicle cargo regulate neuronal excitability.
Datta Chaudhuri A, Dasgheyb RM, DeVine LR, Bi H, Cole RN, Haughey NJ. Datta Chaudhuri A, et al. Glia. 2020 Jan;68(1):128-144. doi: 10.1002/glia.23708. Epub 2019 Aug 30. Glia. 2020. PMID: 31469478
Astrocyte-derived extracellular vesicles (ADEVs) secreted constitutively promote neurite outgrowth and neuronal survival. However, extracellular stimuli can alter the cargo and downstream functions of ADEVs. For example, ADEVs secreted in response to inflammation contain …
Astrocyte-derived extracellular vesicles (ADEVs) secreted constitutively promote neurite outgrowth and neuronal survival. However, extracell …
Targeted Delivery of Adamantylated Peptidoglycan Immunomodulators in Lipid Nanocarriers: NMR Shows That Cargo Fragments Are Available on the Surface.
Ribić R, Manček-Keber M, Chain F, Sinnaeve D, Martins JC, Jerala R, Tomić S, Fehér K. Ribić R, et al. J Phys Chem B. 2020 May 21;124(20):4132-4145. doi: 10.1021/acs.jpcb.0c00029. Epub 2020 May 8. J Phys Chem B. 2020. PMID: 32283934
We present an in-depth investigation of the membrane interactions of peptidoglycan (PGN)-based immune adjuvants designed for lipid-based delivery systems using NMR spectroscopy. The derivatives contain a cargo peptidoglycan (PGN) dipeptide fragment and an adamantyl group, …
We present an in-depth investigation of the membrane interactions of peptidoglycan (PGN)-based immune adjuvants designed for lipid-based del …
Prognostic Value of CD63 Expression in Solid Tumors: A Meta-analysis of the Literature.
Koh HM, Jang BG, Kim DC. Koh HM, et al. In Vivo. 2020 Sep-Oct;34(5):2209-2215. doi: 10.21873/invivo.12031. In Vivo. 2020. PMID: 32871743 Free PMC article. Review.
RESULTS: Five studies with a total of 1,454 patients were included. The HR evaluating CD63 expression on survival was 1.34 (95%CI=0.92-1.97, p=0.129). ...CD63 expression was significantly associated with poor disease-specific survival (HR=1.69, 95% CI=1.15-2.49, p=0 …
RESULTS: Five studies with a total of 1,454 patients were included. The HR evaluating CD63 expression on survival was 1.34 (95%CI=0.9 …
The Inflammatory Cytokine IL-3 Hampers Cardioprotection Mediated by Endothelial Cell-Derived Extracellular Vesicles Possibly via Their Protein Cargo.
Penna C, Femminò S, Tapparo M, Lopatina T, Fladmark KE, Ravera F, Comità S, Alloatti G, Giusti I, Dolo V, Camussi G, Pagliaro P, Brizzi MF. Penna C, et al. Cells. 2020 Dec 23;10(1):13. doi: 10.3390/cells10010013. Cells. 2020. PMID: 33374685 Free PMC article.
Protein profiles of eEV and eEV-IL-3, established using label-free mass spectrometry, demonstrated that IL-3 drives changes in eEV-IL-3 protein cargo. Gene ontology analysis revealed that both eEV and eEV-IL-3 were equipped with full cardioprotective machinery, including t …
Protein profiles of eEV and eEV-IL-3, established using label-free mass spectrometry, demonstrated that IL-3 drives changes in eEV-IL-3 prot …
Circadian processes in the RNA life cycle.
Torres M, Becquet D, Franc JL, François-Bellan AM. Torres M, et al. Wiley Interdiscip Rev RNA. 2018 May;9(3):e1467. doi: 10.1002/wrna.1467. Epub 2018 Feb 9. Wiley Interdiscip Rev RNA. 2018. PMID: 29424086 Review.
While the ability for the endogenous timekeeping system to generate a 24-hr cycle is a cell-autonomous mechanism based on negative autoregulatory feedback loops of transcription and translation involving core-clock genes and their protein products, it is now increasingly e …
While the ability for the endogenous timekeeping system to generate a 24-hr cycle is a cell-autonomous mechanism based on negative au …
Autophagy receptors in developmental clearance of mitochondria.
Novak I, Dikic I. Novak I, et al. Autophagy. 2011 Mar;7(3):301-3. doi: 10.4161/auto.7.3.14509. Autophagy. 2011. PMID: 21206218 Free PMC article. Review.
Recent discoveries of autophagy receptors, which specifically recognize different cellular cargo destined for degradation, have opened a new chapter in the autophagy field. Selective cargo recognition by autophagic machinery is important in the context of cellular h …
Recent discoveries of autophagy receptors, which specifically recognize different cellular cargo destined for degradation, have opene …
A self-assembling amphiphilic peptide nanoparticle for the efficient entrapment of DNA cargoes up to 100 nucleotides in length.
Tarvirdipour S , Schoenenberger CA , Benenson Y , Palivan CG . Tarvirdipour S , et al. Soft Matter. 2020 Feb 12;16(6):1678-1691. doi: 10.1039/c9sm01990a. Soft Matter. 2020. PMID: 31967171
To overcome the low efficiency and cytotoxicity associated with most non-viral DNA delivery systems we developed a purely peptidic self-assembling system that is able to entrap single- and double-stranded DNA of up to 100 nucleotides in length. (HR)3gT peptide design consi …
To overcome the low efficiency and cytotoxicity associated with most non-viral DNA delivery systems we developed a purely peptidic self-asse …
Mitophagy: a complex mechanism of mitochondrial removal.
Novak I. Novak I. Antioxid Redox Signal. 2012 Sep 1;17(5):794-802. doi: 10.1089/ars.2011.4407. Epub 2012 Feb 3. Antioxid Redox Signal. 2012. PMID: 22077334 Review.
RECENT ADVANCES: Recent work is elucidating how mitochondria are recognized for selective mitophagy either by PINK1 and Parkin or mitophagic receptors Nix and Bnip3 and their accompanying modulators. PINK1/Parkin-mediated mitophagy reveals their role of cargo recognition t …
RECENT ADVANCES: Recent work is elucidating how mitochondria are recognized for selective mitophagy either by PINK1 and Parkin or mitophagic …
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