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182 results
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The role of ATM in response to metformin treatment and activation of AMPK.
Woods A, Leiper JM, Carling D. Woods A, et al. Among authors: carling d. Nat Genet. 2012 Mar 28;44(4):360-1. doi: 10.1038/ng.2235. Nat Genet. 2012. PMID: 22456733 No abstract available.
Structure of mammalian AMPK and its regulation by ADP.
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: carling d. Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13. Nature. 2011. PMID: 21399626 Free PMC article.
Structural basis for AMP binding to mammalian AMP-activated protein kinase.
Xiao B, Heath R, Saiu P, Leiper FC, Leone P, Jing C, Walker PA, Haire L, Eccleston JF, Davis CT, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: carling d. Nature. 2007 Sep 27;449(7161):496-500. doi: 10.1038/nature06161. Epub 2007 Sep 12. Nature. 2007. PMID: 17851531
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.
Watt MJ, Dzamko N, Thomas WG, Rose-John S, Ernst M, Carling D, Kemp BE, Febbraio MA, Steinberg GR. Watt MJ, et al. Among authors: carling d. Nat Med. 2006 May;12(5):541-8. doi: 10.1038/nm1383. Epub 2006 Apr 9. Nat Med. 2006. PMID: 16604088
Structural basis of AMPK regulation by small molecule activators.
Xiao B, Sanders MJ, Carmena D, Bright NJ, Haire LF, Underwood E, Patel BR, Heath RB, Walker PA, Hallen S, Giordanetto F, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: carling d. Nat Commun. 2013;4:3017. doi: 10.1038/ncomms4017. Nat Commun. 2013. PMID: 24352254 Free PMC article.
The regulation of AMP-activated protein kinase by upstream kinases.
Carling D, Sanders MJ, Woods A. Carling D, et al. Int J Obes (Lond). 2008 Sep;32 Suppl 4:S55-9. doi: 10.1038/ijo.2008.124. Int J Obes (Lond). 2008. PMID: 18719600 Review.
Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.
Ponticos M, Lu QL, Morgan JE, Hardie DG, Partridge TA, Carling D. Ponticos M, et al. Among authors: carling d. EMBO J. 1998 Mar 16;17(6):1688-99. doi: 10.1093/emboj/17.6.1688. EMBO J. 1998. PMID: 9501090 Free PMC article.
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.
Johanns M, Lai YC, Hsu MF, Jacobs R, Vertommen D, Van Sande J, Dumont JE, Woods A, Carling D, Hue L, Viollet B, Foretz M, Rider MH. Johanns M, et al. Among authors: carling d. Nat Commun. 2016 Mar 8;7:10856. doi: 10.1038/ncomms10856. Nat Commun. 2016. PMID: 26952277 Free PMC article.
The regulation and function of mammalian AMPK-related kinases.
Bright NJ, Thornton C, Carling D. Bright NJ, et al. Among authors: carling d. Acta Physiol (Oxf). 2009 May;196(1):15-26. doi: 10.1111/j.1748-1716.2009.01971.x. Epub 2009 Feb 19. Acta Physiol (Oxf). 2009. PMID: 19245655 Review.
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia.
Marsin AS, Bertrand L, Rider MH, Deprez J, Beauloye C, Vincent MF, Van den Berghe G, Carling D, Hue L. Marsin AS, et al. Among authors: carling d. Curr Biol. 2000 Oct 19;10(20):1247-55. doi: 10.1016/s0960-9822(00)00742-9. Curr Biol. 2000. PMID: 11069105
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