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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities.
Carling D, Clarke PR, Zammit VA, Hardie DG. Carling D, et al. Eur J Biochem. 1989 Dec 8;186(1-2):129-36. doi: 10.1111/j.1432-1033.1989.tb15186.x. Eur J Biochem. 1989. PMID: 2598924
The regulation of AMP-activated protein kinase by upstream kinases.
Carling D, Sanders MJ, Woods A. Carling D, et al. Int J Obes (Lond). 2008 Sep;32 Suppl 4:S55-9. doi: 10.1038/ijo.2008.124. Int J Obes (Lond). 2008. PMID: 18719600 Review.
Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components.
Velasco G, Gómez del Pulgar T, Carling D, Guzmán M. Velasco G, et al. Among authors: carling d. FEBS Lett. 1998 Nov 20;439(3):317-20. doi: 10.1016/s0014-5793(98)01400-8. FEBS Lett. 1998. PMID: 9845345
Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.
Ponticos M, Lu QL, Morgan JE, Hardie DG, Partridge TA, Carling D. Ponticos M, et al. Among authors: carling d. EMBO J. 1998 Mar 16;17(6):1688-99. doi: 10.1093/emboj/17.6.1688. EMBO J. 1998. PMID: 9501090 Free PMC article.
Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle.
Thornton C, Snowden MA, Carling D. Thornton C, et al. Among authors: carling d. J Biol Chem. 1998 May 15;273(20):12443-50. doi: 10.1074/jbc.273.20.12443. J Biol Chem. 1998. PMID: 9575201
AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.
Salt I, Celler JW, Hawley SA, Prescott A, Woods A, Carling D, Hardie DG. Salt I, et al. Among authors: carling d. Biochem J. 1998 Aug 15;334 ( Pt 1)(Pt 1):177-87. doi: 10.1042/bj3340177. Biochem J. 1998. PMID: 9693118 Free PMC article.
Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro.
Woods A, Cheung PC, Smith FC, Davison MD, Scott J, Beri RK, Carling D. Woods A, et al. Among authors: carling d. J Biol Chem. 1996 Apr 26;271(17):10282-90. doi: 10.1074/jbc.271.17.10282. J Biol Chem. 1996. PMID: 8626596
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase.
Hawley SA, Davison M, Woods A, Davies SP, Beri RK, Carling D, Hardie DG. Hawley SA, et al. Among authors: carling d. J Biol Chem. 1996 Nov 1;271(44):27879-87. doi: 10.1074/jbc.271.44.27879. J Biol Chem. 1996. PMID: 8910387
., Carling, D., and Hardie, D. G. (1995) J. Biol. Chem. 270, 27186-27191)....
., Carling, D., and Hardie, D. G. (1995) J. Biol. Chem. 270, 27186-27191)....
AMP-activated protein kinase and the metabolic syndrome.
Fryer LG, Carling D. Fryer LG, et al. Among authors: carling d. Biochem Soc Trans. 2005 Apr;33(Pt 2):362-6. doi: 10.1042/BST0330362. Biochem Soc Trans. 2005. PMID: 15787607 Review.
Bypassing the glucose/fatty acid cycle: AMP-activated protein kinase.
Carling D, Fryer LG, Woods A, Daniel T, Jarvie SL, Whitrow H. Carling D, et al. Biochem Soc Trans. 2003 Dec;31(Pt 6):1157-60. doi: 10.1042/bst0311157. Biochem Soc Trans. 2003. PMID: 14641016 Review.
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