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Dopamine receptor-mediated hypothermia induced in rats by (+)-, but not by (-)-3-PPP.
Hjorth S, Carlsson A, Clark D, Svensson K, Sanchez D. Hjorth S, et al. Among authors: carlsson a. Eur J Pharmacol. 1985 Jan 8;107(3):299-304. doi: 10.1016/0014-2999(85)90254-7. Eur J Pharmacol. 1985. PMID: 3979430
Although approximately 30 times less potent than apomorphine, (+)-3-PPP induced a clearcut, dose-dependent and haloperidol/pimozide-reversible hypothermia. In contrast, the (-)-enantiomer per se lacked a significant effect upon rat body temperature. However, (-)-3-P …
Although approximately 30 times less potent than apomorphine, (+)-3-PPP induced a clearcut, dose-dependent and haloperidol/pimozide-r …
1,417 results