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2002 4
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2011 5
2012 5
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109 results

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Page 1
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.
Hu H, Gehart H, Artegiani B, LÖpez-Iglesias C, Dekkers F, Basak O, van Es J, Chuva de Sousa Lopes SM, Begthel H, Korving J, van den Born M, Zou C, Quirk C, Chiriboga L, Rice CM, Ma S, Rios A, Peters PJ, de Jong YP, Clevers H. Hu H, et al. Among authors: lopez iglesias c. Cell. 2018 Nov 29;175(6):1591-1606.e19. doi: 10.1016/j.cell.2018.11.013. Cell. 2018. PMID: 30500538 Free article.
Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation.
He GW, Lin L, DeMartino J, Zheng X, Staliarova N, Dayton T, Begthel H, van de Wetering WJ, Bodewes E, van Zon J, Tans S, Lopez-Iglesias C, Peters PJ, Wu W, Kotlarz D, Klein C, Margaritis T, Holstege F, Clevers H. He GW, et al. Among authors: lopez iglesias c. Cell Stem Cell. 2022 Sep 1;29(9):1333-1345.e6. doi: 10.1016/j.stem.2022.08.002. Epub 2022 Aug 23. Cell Stem Cell. 2022. PMID: 36002022 Free PMC article.
Human fetal brain self-organizes into long-term expanding organoids.
Hendriks D, Pagliaro A, Andreatta F, Ma Z, van Giessen J, Massalini S, López-Iglesias C, van Son GJF, DeMartino J, Damen JMA, Zoutendijk I, Staliarova N, Bredenoord AL, Holstege FCP, Peters PJ, Margaritis T, Chuva de Sousa Lopes S, Wu W, Clevers H, Artegiani B. Hendriks D, et al. Among authors: lopez iglesias c. Cell. 2024 Feb 1;187(3):712-732.e38. doi: 10.1016/j.cell.2023.12.012. Epub 2024 Jan 8. Cell. 2024. PMID: 38194967 Free article.
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.
Hendriks D, Brouwers JF, Hamer K, Geurts MH, Luciana L, Massalini S, López-Iglesias C, Peters PJ, Rodríguez-Colman MJ, Chuva de Sousa Lopes S, Artegiani B, Clevers H. Hendriks D, et al. Among authors: lopez iglesias c. Nat Biotechnol. 2023 Nov;41(11):1567-1581. doi: 10.1038/s41587-023-01680-4. Epub 2023 Feb 23. Nat Biotechnol. 2023. PMID: 36823355 Free PMC article.
Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation.
Lin L, DeMartino J, Wang D, van Son GJF, van der Linden R, Begthel H, Korving J, Andersson-Rolf A, van den Brink S, Lopez-Iglesias C, van de Wetering WJ, Balwierz A, Margaritis T, van de Wetering M, Peters PJ, Drost J, van Es JH, Clevers H. Lin L, et al. Among authors: lopez iglesias c. Science. 2023 Oct 27;382(6669):451-458. doi: 10.1126/science.adi2246. Epub 2023 Oct 26. Science. 2023. PMID: 37883554
Tuft cells act as regenerative stem cells in the human intestine.
Huang L, Bernink JH, Giladi A, Krueger D, van Son GJF, Geurts MH, Busslinger G, Lin L, Begthel H, Zandvliet M, Buskens CJ, Bemelman WA, López-Iglesias C, Peters PJ, Clevers H. Huang L, et al. Among authors: lopez iglesias c. Nature. 2024 Oct;634(8035):929-935. doi: 10.1038/s41586-024-07952-6. Epub 2024 Oct 2. Nature. 2024. PMID: 39358509 Free PMC article.
Fibril structure of amyloid-β(1-42) by cryo-electron microscopy.
Gremer L, Schölzel D, Schenk C, Reinartz E, Labahn J, Ravelli RBG, Tusche M, Lopez-Iglesias C, Hoyer W, Heise H, Willbold D, Schröder GF. Gremer L, et al. Among authors: lopez iglesias c. Science. 2017 Oct 6;358(6359):116-119. doi: 10.1126/science.aao2825. Epub 2017 Sep 7. Science. 2017. PMID: 28882996 Free PMC article.
Description and functional validation of human enteroendocrine cell sensors.
Beumer J, Geurts MH, Geurts V, Andersson-Rolf A, Akkerman N, Völlmy F, Krueger D, Busslinger GA, Martínez-Silgado A, Boot C, Yousef Yengej FA, Puschhof J, Van de Wetering WJ, Knoops K, López-Iglesias C, Peters PJ, Vivié JA, Mooijman D, van Es JH, Clevers H. Beumer J, et al. Among authors: lopez iglesias c. Science. 2024 Oct 18;386(6719):341-348. doi: 10.1126/science.adl1460. Epub 2024 Oct 17. Science. 2024. PMID: 39418382 Free PMC article.
High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells.
Beumer J, Puschhof J, Bauzá-Martinez J, Martínez-Silgado A, Elmentaite R, James KR, Ross A, Hendriks D, Artegiani B, Busslinger GA, Ponsioen B, Andersson-Rolf A, Saftien A, Boot C, Kretzschmar K, Geurts MH, Bar-Ephraim YE, Pleguezuelos-Manzano C, Post Y, Begthel H, van der Linden F, Lopez-Iglesias C, van de Wetering WJ, van der Linden R, Peters PJ, Heck AJR, Goedhart J, Snippert H, Zilbauer M, Teichmann SA, Wu W, Clevers H. Beumer J, et al. Among authors: lopez iglesias c. Cell. 2020 Jun 11;181(6):1291-1306.e19. doi: 10.1016/j.cell.2020.04.036. Epub 2020 May 13. Cell. 2020. PMID: 32407674 Free article.
Human conjunctiva organoids to study ocular surface homeostasis and disease.
Bannier-Hélaouët M, Korving J, Ma Z, Begthel H, Giladi A, Lamers MM, van de Wetering WJ, Yawata N, Yawata M, LaPointe VLS, Dickman MM, Kalmann R, Imhoff SM, van Es JH, López-Iglesias C, Peters PJ, Haagmans BL, Wu W, Clevers H. Bannier-Hélaouët M, et al. Among authors: lopez iglesias c. Cell Stem Cell. 2024 Feb 1;31(2):227-243.e12. doi: 10.1016/j.stem.2023.12.008. Epub 2024 Jan 11. Cell Stem Cell. 2024. PMID: 38215738 Free article.
109 results