Carmichael J - Search Results

1

The molecular biology of Huntington's disease.

Ho LW, Carmichael J, Swartz J, Wyttenbach A, Rankin J, Rubinsztein DC. Ho LW, et al. Among authors: carmichael j. Psychol Med. 2001 Jan;31(1):3-14. doi: 10.1017/s0033291799002871. Psychol Med. 2001. PMID: 11200958 Review.

2

The bacterial chaperonin GroEL requires GroES to reduce aggregation and cell death in a COS-7 cell model of Huntington's disease.

Carmichael J, Vacher C, Rubinsztein DC. Carmichael J, et al. Neurosci Lett. 2002 Sep 27;330(3):270-4. doi: 10.1016/s0304-3940(02)00770-x. Neurosci Lett. 2002. PMID: 12270644

3

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.

Wyttenbach A, Sauvageot O, Carmichael J, Diaz-Latoud C, Arrigo AP, Rubinsztein DC. Wyttenbach A, et al. Among authors: carmichael j. Hum Mol Genet. 2002 May 1;11(9):1137-51. doi: 10.1093/hmg/11.9.1137. Hum Mol Genet. 2002. PMID: 11978772

4

Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation.

Carmichael J, Sugars KL, Bao YP, Rubinsztein DC. Carmichael J, et al. J Biol Chem. 2002 Sep 13;277(37):33791-8. doi: 10.1074/jbc.M204861200. Epub 2002 Jul 3. J Biol Chem. 2002. PMID: 12097329

5

Huntington's disease: molecular basis of neurodegeneration.

Rubinsztein DC, Carmichael J. Rubinsztein DC, et al. Among authors: carmichael j. Expert Rev Mol Med. 2003 Aug 22;5(20):1-21. doi: 10.1017/S1462399403006549. Expert Rev Mol Med. 2003. PMID: 14585171 Review.

6

Huntington's disease: from pathology and genetics to potential therapies.

Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, Rose C, Krishna G, Davies JE, Ttofi E, Underwood BR, Rubinsztein DC. Imarisio S, et al. Among authors: carmichael j. Biochem J. 2008 Jun 1;412(2):191-209. doi: 10.1042/BJ20071619. Biochem J. 2008. PMID: 18466116 Review.

7

Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease.

Carss KJ, Arno G, Erwood M, Stephens J, Sanchis-Juan A, Hull S, Megy K, Grozeva D, Dewhurst E, Malka S, Plagnol V, Penkett C, Stirrups K, Rizzo R, Wright G, Josifova D, Bitner-Glindzicz M, Scott RH, Clement E, Allen L, Armstrong R, Brady AF, Carmichael J, Chitre M, Henderson RHH, Hurst J, MacLaren RE, Murphy E, Paterson J, Rosser E, Thompson DA, Wakeling E, Ouwehand WH, Michaelides M, Moore AT; NIHR-BioResource Rare Diseases Consortium, Webster AR, Raymond FL. Carss KJ, et al. Among authors: carmichael j. Am J Hum Genet. 2017 Jan 5;100(1):75-90. doi: 10.1016/j.ajhg.2016.12.003. Epub 2016 Dec 29. Am J Hum Genet. 2017. PMID: 28041643 Free PMC article.

8

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.

Wyttenbach A, Swartz J, Kita H, Thykjaer T, Carmichael J, Bradley J, Brown R, Maxwell M, Schapira A, Orntoft TF, Kato K, Rubinsztein DC. Wyttenbach A, et al. Among authors: carmichael j. Hum Mol Genet. 2001 Aug 15;10(17):1829-45. doi: 10.1093/hmg/10.17.1829. Hum Mol Genet. 2001. PMID: 11532992

9

Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease.

Carmichael J, Chatellier J, Woolfson A, Milstein C, Fersht AR, Rubinsztein DC. Carmichael J, et al. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9701-5. doi: 10.1073/pnas.170280697. Proc Natl Acad Sci U S A. 2000. PMID: 10920207 Free PMC article.

10

Modulation of polyglutamine-induced cell death by genes identified by expression profiling.

Kita H, Carmichael J, Swartz J, Muro S, Wyttenbach A, Matsubara K, Rubinsztein DC, Kato K. Kita H, et al. Among authors: carmichael j. Hum Mol Genet. 2002 Sep 15;11(19):2279-87. doi: 10.1093/hmg/11.19.2279. Hum Mol Genet. 2002. PMID: 12217956

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