Carrà G - Search Results

1

Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Calpha,alpha-dialkylated amino acids.

Arduin M, Spagnolo B, Calò G, Guerrini R, Carrà G, Fischetti C, Trapella C, Marzola E, McDonald J, Lambert DG, Regoli D, Salvadori S. Arduin M, et al. Among authors: carra g. Bioorg Med Chem. 2007 Jul 1;15(13):4434-43. doi: 10.1016/j.bmc.2007.04.026. Epub 2007 Apr 24. Bioorg Med Chem. 2007. PMID: 17490886

2

[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.

Carrà G, Rizzi A, Guerrini R, Barnes TA, McDonald J, Hebbes CP, Mela F, Kenigs VA, Marzola G, Rizzi D, Gavioli E, Zucchini S, Regoli D, Morari M, Salvadori S, Rowbotham DJ, Lambert DG, Kapusta DR, Calo' G. Carrà G, et al. J Pharmacol Exp Ther. 2005 Mar;312(3):1114-23. doi: 10.1124/jpet.104.077339. Epub 2004 Oct 27. J Pharmacol Exp Ther. 2005. PMID: 15509719

3

N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands.

Guerrini R, Caló G, Lambert DG, Carrá G, Arduin M, Barnes TA, McDonald J, Rizzi D, Trapella C, Marzola E, Rowbotham DJ, Regoli D, Salvadori S. Guerrini R, et al. Among authors: carra g. J Med Chem. 2005 Mar 10;48(5):1421-7. doi: 10.1021/jm040106v. J Med Chem. 2005. PMID: 15743186

4

Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.

Trapella C, Guerrini R, Piccagli L, Calo' G, Carra' G, Spagnolo B, Rubini S, Fanton G, Hebbes C, McDonald J, Lambert DG, Regoli D, Salvadori S. Trapella C, et al. Among authors: carra g. Bioorg Med Chem. 2006 Feb 1;14(3):692-704. doi: 10.1016/j.bmc.2005.08.049. Epub 2005 Oct 3. Bioorg Med Chem. 2006. PMID: 16202610

5

Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vitro studies.

Spagnolo B, Carrà G, Fantin M, Fischetti C, Hebbes C, McDonald J, Barnes TA, Rizzi A, Trapella C, Fanton G, Morari M, Lambert DG, Regoli D, Calò G. Spagnolo B, et al. Among authors: carra g. J Pharmacol Exp Ther. 2007 Jun;321(3):961-7. doi: 10.1124/jpet.106.116764. Epub 2007 Feb 28. J Pharmacol Exp Ther. 2007. PMID: 17329552

6

Nonpeptide/peptide chimeric ligands for the nociceptin/orphanin FQ receptor: design, synthesis and in vitro pharmacological activity.

Guerrini R, Carra' G, Calo' G, Trapella C, Marzola E, Rizzi D, Regoli D, Salvadori S. Guerrini R, et al. Among authors: carra g. J Pept Res. 2004 Jun;63(6):477-84. doi: 10.1111/j.1399-3011.2004.00157.x. J Pept Res. 2004. PMID: 15175020

7

Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2.

Carra' G, Calo' G, Spagnolo B, Guerrini R, Arduin M, Marzola E, Trapella C, Regoli D, Salvadori S. Carra' G, et al. J Pept Res. 2005 Jul;66(1):39-47. doi: 10.1111/j.1399-3011.2005.00272.x. J Pept Res. 2005. PMID: 15946194

8

The interaction of highly helical structural mutants with the NOP receptor discloses the role of the address domain of nociceptin/orphanin FQ.

Tancredi T, Carrà G, Guerrini R, Arduin M, Calò G, Regoli D, Salvadori S, Temussi PA. Tancredi T, et al. Among authors: carra g. Chemistry. 2005 Mar 18;11(7):2061-70. doi: 10.1002/chem.200401095. Chemistry. 2005. PMID: 15712334

9

Pharmacological profile of the cyclic nociceptin/orphanin FQ analogues c[Cys10,14]N/OFQ(1-14)NH2 and c[Nphe1,Cys10,14]N/OFQ(1-14)NH2.

Kitayama M, Barnes TA, Carra G, McDonald J, Calo G, Guerrini R, Rowbotham DJ, Smith G, Lambert DG. Kitayama M, et al. Among authors: carra g. Naunyn Schmiedebergs Arch Pharmacol. 2003 Dec;368(6):528-37. doi: 10.1007/s00210-003-0821-5. Epub 2003 Nov 4. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14598020

10

ACE inhibition modulates endothelial apoptosis and renewal via endothelial progenitor cells in patients with acute coronary syndromes.

Cangiano E, Marchesini J, Campo G, Francolini G, Fortini C, Carrà G, Miccoli M, Ceconi C, Tavazzi L, Ferrari R. Cangiano E, et al. Among authors: carra g. Am J Cardiovasc Drugs. 2011 Jun 1;11(3):189-98. doi: 10.2165/11589400-000000000-00000. Am J Cardiovasc Drugs. 2011. PMID: 21619382 Clinical Trial.

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