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Inhibitory conformation of the reactive loop of alpha 1-antitrypsin.
Elliott PR, Lomas DA, Carrell RW, Abrahams JP. Elliott PR, et al. Among authors: carrell rw. Nat Struct Biol. 1996 Aug;3(8):676-81. doi: 10.1038/nsb0896-676. Nat Struct Biol. 1996. PMID: 8756325
What can Drosophila tell us about serpins, thrombosis and dementia?
Carrell R, Corral J. Carrell R, et al. Bioessays. 2004 Jan;26(1):1-5. doi: 10.1002/bies.10407. Bioessays. 2004. PMID: 14696034 Review.
Serpins as hormone carriers: modulation of release.
Carrell R, Qi X, Zhou A. Carrell R, et al. Methods Enzymol. 2011;501:89-103. doi: 10.1016/B978-0-12-385950-1.00006-7. Methods Enzymol. 2011. PMID: 22078532
Murine serpin 2A is a redox-sensitive intracellular protein.
Morris EC, Dafforn TR, Forsyth SL, Missen MA, Horvath AJ, Hampson L, Hampson IN, Currie G, Carrell RW, Coughlin PB. Morris EC, et al. Among authors: carrell rw. Biochem J. 2003 Apr 1;371(Pt 1):165-73. doi: 10.1042/BJ20021567. Biochem J. 2003. PMID: 12470299 Free PMC article.
Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol.
Zhou A, Stein PE, Huntington JA, Carrell RW. Zhou A, et al. Among authors: carrell rw. J Biol Chem. 2003 Apr 25;278(17):15116-22. doi: 10.1074/jbc.M211663200. Epub 2003 Feb 10. J Biol Chem. 2003. PMID: 12578831
Alpha1-antitrypsin deficiency--a model for conformational diseases.
Carrell RW, Lomas DA. Carrell RW, et al. N Engl J Med. 2002 Jan 3;346(1):45-53. doi: 10.1056/NEJMra010772. N Engl J Med. 2002. PMID: 11778003 Review. No abstract available.
Serpinopathies and the conformational dementias.
Lomas DA, Carrell RW. Lomas DA, et al. Among authors: carrell rw. Nat Rev Genet. 2002 Oct;3(10):759-68. doi: 10.1038/nrg907. Nat Rev Genet. 2002. PMID: 12360234 Review.
Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
Yan Y, Zhou A, Carrell RW, Read RJ. Yan Y, et al. Among authors: carrell rw. J Biol Chem. 2019 Feb 15;294(7):2353-2364. doi: 10.1074/jbc.RA118.006608. Epub 2018 Dec 18. J Biol Chem. 2019. PMID: 30563843 Free PMC article.
Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X.
Wei Z, Yan Y, Carrell RW, Zhou A. Wei Z, et al. Among authors: carrell rw. Blood. 2009 Oct 22;114(17):3662-7. doi: 10.1182/blood-2009-04-210021. Epub 2009 Jun 15. Blood. 2009. PMID: 19528533 Free PMC article.
The S-to-R transition of corticosteroid-binding globulin and the mechanism of hormone release.
Zhou A, Wei Z, Stanley PL, Read RJ, Stein PE, Carrell RW. Zhou A, et al. Among authors: carrell rw. J Mol Biol. 2008 Jun 27;380(1):244-51. doi: 10.1016/j.jmb.2008.05.012. Epub 2008 May 14. J Mol Biol. 2008. PMID: 18513745
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