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28 days of creatine nitrate supplementation is apparently safe in healthy individuals.
Joy JM, Lowery RP, Falcone PH, Mosman MM, Vogel RM, Carson LR, Tai CY, Choate D, Kimber D, Ormes JA, Wilson JM, Moon JR. Joy JM, et al. Among authors: carson lr. J Int Soc Sports Nutr. 2014 Dec 20;11(1):60. doi: 10.1186/s12970-014-0060-9. eCollection 2014. J Int Soc Sports Nutr. 2014. PMID: 25589898 Free PMC article.
Ingesting a preworkout supplement containing caffeine, creatine, β-alanine, amino acids, and B vitamins for 28 days is both safe and efficacious in recreationally active men.
Kendall KL, Moon JR, Fairman CM, Spradley BD, Tai CY, Falcone PH, Carson LR, Mosman MM, Joy JM, Kim MP, Serrano ER, Esposito EN. Kendall KL, et al. Among authors: carson lr. Nutr Res. 2014 May;34(5):442-9. doi: 10.1016/j.nutres.2014.04.003. Epub 2014 Apr 13. Nutr Res. 2014. PMID: 24916558 Clinical Trial.