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Humanization of an anti-p185HER2 antibody for human cancer therapy.
Carter P, Presta L, Gorman CM, Ridgway JB, Henner D, Wong WL, Rowland AM, Kotts C, Carver ME, Shepard HM. Carter P, et al. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4285-9. doi: 10.1073/pnas.89.10.4285. Proc Natl Acad Sci U S A. 1992. PMID: 1350088 Free PMC article.
Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments.
Kelley RF, O'Connell MP, Carter P, Presta L, Eigenbrot C, Covarrubias M, Snedecor B, Bourell JH, Vetterlein D. Kelley RF, et al. Among authors: carter p. Biochemistry. 1992 Jun 23;31(24):5434-41. doi: 10.1021/bi00139a003. Biochemistry. 1992. PMID: 1351741
The murine monoclonal antibody 4D5 (anti-p185HER2) inhibits the proliferation of human tumor cells overexpressing p185HER2 in vitro and has been "humanized" [Carter, P., Presta, L., Gorman, C. M., Ridgway, J. B. B., Henner, D., Wong, W....
The murine monoclonal antibody 4D5 (anti-p185HER2) inhibits the proliferation of human tumor cells overexpressing p185HER2 in vitro and has …
1,404 results