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AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.
Davies BR, Logie A, McKay JS, Martin P, Steele S, Jenkins R, Cockerill M, Cartlidge S, Smith PD. Davies BR, et al. Mol Cancer Ther. 2007 Aug;6(8):2209-19. doi: 10.1158/1535-7163.MCT-07-0231. Mol Cancer Ther. 2007. PMID: 17699718
Substrate selection and processing in endocytosis.
Lloyd JB, Pratten MK, Duncan R, Kooistra T, Cartlidge SA. Lloyd JB, et al. Among authors: cartlidge sa. Biochem Soc Trans. 1984 Dec;12(6):977-8. doi: 10.1042/bst0120977. Biochem Soc Trans. 1984. PMID: 6530046 No abstract available.