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Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.
Tomar D, Jaña F, Dong Z, Quinn WJ 3rd, Jadiya P, Breves SL, Daw CC, Srikantan S, Shanmughapriya S, Nemani N, Carvalho E, Tripathi A, Worth AM, Zhang X, Razmpour R, Seelam A, Rhode S, Mehta AV, Murray M, Slade D, Ramirez SH, Mishra P, Gerhard GS, Caplan J, Norton L, Sharma K, Rajan S, Balciunas D, Wijesinghe DS, Ahima RS, Baur JA, Madesh M. Tomar D, et al. Among authors: carvalho e. Cell Rep. 2019 Mar 26;26(13):3709-3725.e7. doi: 10.1016/j.celrep.2019.02.107. Cell Rep. 2019. PMID: 30917323 Free PMC article.
Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.
Dong Z, Shanmughapriya S, Tomar D, Siddiqui N, Lynch S, Nemani N, Breves SL, Zhang X, Tripathi A, Palaniappan P, Riitano MF, Worth AM, Seelam A, Carvalho E, Subbiah R, Jaña F, Soboloff J, Peng Y, Cheung JY, Joseph SK, Caplan J, Rajan S, Stathopulos PB, Madesh M. Dong Z, et al. Among authors: carvalho e. Mol Cell. 2017 Mar 16;65(6):1014-1028.e7. doi: 10.1016/j.molcel.2017.01.032. Epub 2017 Mar 2. Mol Cell. 2017. PMID: 28262504 Free PMC article.
MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress.
Nemani N, Carvalho E, Tomar D, Dong Z, Ketschek A, Breves SL, Jaña F, Worth AM, Heffler J, Palaniappan P, Tripathi A, Subbiah R, Riitano MF, Seelam A, Manfred T, Itoh K, Meng S, Sesaki H, Craigen WJ, Rajan S, Shanmughapriya S, Caplan J, Prosser BL, Gill DL, Stathopulos PB, Gallo G, Chan DC, Mishra P, Madesh M. Nemani N, et al. Among authors: carvalho e. Cell Rep. 2018 Apr 24;23(4):1005-1019. doi: 10.1016/j.celrep.2018.03.098. Cell Rep. 2018. PMID: 29694881 Free PMC article.
Regulation of Ca2+ exchanges and signaling in mitochondria.
Carvalho EJ, Stathopulos PB, Madesh M. Carvalho EJ, et al. Curr Opin Physiol. 2020 Oct;17:197-206. doi: 10.1016/j.cophys.2020.08.010. Epub 2020 Aug 23. Curr Opin Physiol. 2020. PMID: 33103015 Free PMC article.
FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation.
Shanmughapriya S, Tomar D, Dong Z, Slovik KJ, Nemani N, Natarajaseenivasan K, Carvalho E, Lu C, Corrigan K, Garikipati VNS, Ibetti J, Rajan S, Barrero C, Chuprun K, Kishore R, Merali S, Tian Y, Yang W, Madesh M. Shanmughapriya S, et al. Among authors: carvalho e. Nat Commun. 2018 Aug 29;9(1):3449. doi: 10.1038/s41467-018-05856-4. Nat Commun. 2018. PMID: 30158529 Free PMC article.
A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury.
Woods JJ, Nemani N, Shanmughapriya S, Kumar A, Zhang M, Nathan SR, Thomas M, Carvalho E, Ramachandran K, Srikantan S, Stathopulos PB, Wilson JJ, Madesh M. Woods JJ, et al. Among authors: carvalho e. ACS Cent Sci. 2019 Jan 23;5(1):153-166. doi: 10.1021/acscentsci.8b00773. Epub 2019 Jan 4. ACS Cent Sci. 2019. PMID: 30693334 Free PMC article.
Osteogenic differentiation of human mesenchymal stem cells on electroactive substrates.
Tamaño-Machiavello MN, Carvalho EO, Correia D, Cordón L, Lanceros-Méndez S, Sempere A, Sabater I Serra R, Ribelles JLG. Tamaño-Machiavello MN, et al. Among authors: carvalho eo. Heliyon. 2024 Mar 29;10(7):e28880. doi: 10.1016/j.heliyon.2024.e28880. eCollection 2024 Apr 15. Heliyon. 2024. PMID: 38601667 Free PMC article.
1,724 results