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NAT2*12A (803A-->G) codes for rapid arylamine n-acetylation in humans.
Cascorbi I, Brockmöller J, Bauer S, Reum T, Roots I. Cascorbi I, et al. Pharmacogenetics. 1996 Jun;6(3):257-9. doi: 10.1097/00008571-199606000-00009. Pharmacogenetics. 1996. PMID: 8807666 No abstract available.
Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).
Bruhn C, Brockmöller J, Cascorbi I, Roots I, Borchert HH. Bruhn C, et al. Among authors: cascorbi i. Biochem Pharmacol. 1999 Dec 1;58(11):1759-64. doi: 10.1016/s0006-2952(99)00269-5. Biochem Pharmacol. 1999. PMID: 10571250
Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry.
Dettling M, Schaub RT, Mueller-Oerlinghausen B, Roots I, Cascorbi I. Dettling M, et al. Among authors: cascorbi i. Pharmacogenetics. 2001 Mar;11(2):135-41. doi: 10.1097/00008571-200103000-00004. Pharmacogenetics. 2001. PMID: 11266078
Allelic variants of human cytochrome P450 1A1 (CYP1A1): effect of T461N and I462V substitutions on steroid hydroxylase specificity.
Schwarz D, Kisselev P, Schunck WH, Chernogolov A, Boidol W, Cascorbi I, Roots I. Schwarz D, et al. Among authors: cascorbi i. Pharmacogenetics. 2000 Aug;10(6):519-30. doi: 10.1097/00008571-200008000-00005. Pharmacogenetics. 2000. PMID: 10975606
Pitfalls in N-acetyltransferase 2 genotyping.
Cascorbi I, Roots I. Cascorbi I, et al. Pharmacogenetics. 1999 Feb;9(1):123-7. doi: 10.1097/00008571-199902000-00016. Pharmacogenetics. 1999. PMID: 10208651
High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/Msp-GSTM1*0/*0 genotypes.
Rojas M, Alexandrov K, Cascorbi I, Brockmöller J, Likhachev A, Pozharisski K, Bouvier G, Auburtin G, Mayer L, Kopp-Schneider A, Roots I, Bartsch H. Rojas M, et al. Among authors: cascorbi i. Pharmacogenetics. 1998 Apr;8(2):109-18. Pharmacogenetics. 1998. PMID: 10022748
Association of arylamine N-acetyltransferases NAT1 and NAT2 genotypes to laryngeal cancer risk.
Henning S, Cascorbi I, Münchow B, Jahnke V, Roots I. Henning S, et al. Among authors: cascorbi i. Pharmacogenetics. 1999 Feb;9(1):103-11. Pharmacogenetics. 1999. PMID: 10208649
Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT1*10.
Cascorbi I, Roots I, Brockmöller J. Cascorbi I, et al. Cancer Res. 2001 Jul 1;61(13):5051-6. Cancer Res. 2001. PMID: 11431340
High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease.
Stangl K, Cascorbi I, Laule M, Klein T, Stangl V, Rost S, Wernecke KD, Felix SB, Bindereif A, Baumann G, Roots I. Stangl K, et al. Among authors: cascorbi i. Pharmacogenetics. 2000 Mar;10(2):133-40. doi: 10.1097/00008571-200003000-00005. Pharmacogenetics. 2000. PMID: 10762001
Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease.
Cascorbi I, Laule M, Mrozikiewicz PM, Mrozikiewicz A, Andel C, Baumann G, Roots I, Stangl K. Cascorbi I, et al. Pharmacogenetics. 1999 Dec;9(6):755-61. doi: 10.1097/00008571-199912000-00010. Pharmacogenetics. 1999. PMID: 10634138
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