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Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development.
Phillips TJ, Scott H, Menassa DA, Bignell AL, Sood A, Morton JS, Akagi T, Azuma K, Rogers MF, Gilmore CE, Inman GJ, Grant S, Chung Y, Aljunaidy MM, Cooke CL, Steinkraus BR, Pocklington A, Logan A, Collett GP, Kemp H, Holmans PA, Murphy MP, Fulga TA, Coney AM, Akashi M, Davidge ST, Case CP. Phillips TJ, et al. Among authors: case cp. Sci Rep. 2017 Aug 22;7(1):9079. doi: 10.1038/s41598-017-06300-1. Sci Rep. 2017. PMID: 28831049 Free PMC article.
In vitro placenta barrier model using primary human trophoblasts, underlying connective tissue and vascular endothelium.
Nishiguchi A, Gilmore C, Sood A, Matsusaki M, Collett G, Tannetta D, Sargent IL, McGarvey J, Halemani ND, Hanley J, Day F, Grant S, Murdoch-Davis C, Kemp H, Verkade P, Aplin JD, Akashi M, Case CP. Nishiguchi A, et al. Among authors: case cp. Biomaterials. 2019 Feb;192:140-148. doi: 10.1016/j.biomaterials.2018.08.025. Epub 2018 Aug 25. Biomaterials. 2019. PMID: 30448698
Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.
Curtis DJ, Sood A, Phillips TJ, Leinster VH, Nishiguchi A, Coyle C, Lacharme-Lora L, Beaumont O, Kemp H, Goodall R, Cornes L, Giugliano M, Barone RA, Matsusaki M, Akashi M, Tanaka HY, Kano M, McGarvey J, Halemani ND, Simon K, Keehan R, Ind W, Masters T, Grant S, Athwal S, Collett G, Tannetta D, Sargent IL, Scull-Brown E, Liu X, Aquilina K, Cohen N, Lane JD, Thoresen M, Hanley J, Randall A, Case CP. Curtis DJ, et al. Among authors: case cp. Exp Neurol. 2014 Nov;261:386-95. doi: 10.1016/j.expneurol.2014.05.003. Epub 2014 May 10. Exp Neurol. 2014. PMID: 24818543
72 results