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Tacrolimus use in lupus nephritis: A systematic review and meta-analysis.
Hannah J, Casian A, D'Cruz D. Hannah J, et al. Among authors: casian a. Autoimmun Rev. 2016 Jan;15(1):93-101. doi: 10.1016/j.autrev.2015.09.006. Epub 2015 Sep 30. Autoimmun Rev. 2016. PMID: 26427983 Review.
Intravenous cyclophosphamide and plasmapheresis in dialysis-dependent ANCA-associated vasculitis.
Pepper RJ, Chanouzas D, Tarzi R, Little MA, Casian A, Walsh M, Pusey CD, Harper L, Salama AD; European Vasculitis Study (EUVAS) investigators. Pepper RJ, et al. Clin J Am Soc Nephrol. 2013 Feb;8(2):219-24. doi: 10.2215/CJN.03680412. Epub 2012 Nov 15. Clin J Am Soc Nephrol. 2013. PMID: 23160261 Free PMC article.
BACKGROUND AND OBJECTIVES: Induction therapy with oral cyclophosphamide (CYP) has been a mainstay of treatment in patients with severe renal failure secondary to ANCA-associated vasculitis (AAV). ...Four patients subsequently reached ESRD at a median time of 83 days …
BACKGROUND AND OBJECTIVES: Induction therapy with oral cyclophosphamide (CYP) has been a mainstay of treatment in patients with sever …
Clinical associations with venous thromboembolism in anti-neutrophil cytoplasm antibody-associated vasculitides.
Kronbichler A, Leierer J, Leierer G, Mayer G, Casian A, Höglund P, Westman K, Jayne D; European Vasculitis Society. Kronbichler A, et al. Among authors: casian a. Rheumatology (Oxford). 2017 May 1;56(5):704-708. doi: 10.1093/rheumatology/kew465. Rheumatology (Oxford). 2017. PMID: 28053275 Clinical Trial.
Current modalities in the diagnosis of pulmonary vasculitis.
Casian A, Jayne D. Casian A, et al. Expert Opin Med Diagn. 2012 Nov;6(6):499-516. doi: 10.1517/17530059.2012.697895. Epub 2012 Jun 19. Expert Opin Med Diagn. 2012. PMID: 23480833
INTRODUCTION: This review addresses the pulmonary manifestations of the vasculitides, with a focus on diagnostic modalities. ...AREAS COVERED: The diagnostic modalities in the pulmonary vasculitides are reviewed, with a focus on primary systemic vasculitis. ...
INTRODUCTION: This review addresses the pulmonary manifestations of the vasculitides, with a focus on diagnostic modalities. ...AREAS …
Management of alveolar hemorrhage in lung vasculitides.
Casian A, Jayne D. Casian A, et al. Semin Respir Crit Care Med. 2011 Jun;32(3):335-45. doi: 10.1055/s-0031-1279830. Epub 2011 Jun 14. Semin Respir Crit Care Med. 2011. PMID: 21674419
These interventions have developed empirically supported by a theoretical rationale but have not been validated by randomized clinical trials. ...A minority of cases develop on a background of pulmonary fibrosis, or progressive pulmonary fibrosis develops aft …
These interventions have developed empirically supported by a theoretical rationale but have not been validated by randomized clinica …
Plasma exchange in the treatment of Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and renal limited vasculitis.
Casian A, Jayne D. Casian A, et al. Curr Opin Rheumatol. 2011 Jan;23(1):12-7. doi: 10.1097/BOR.0b013e32834120c1. Curr Opin Rheumatol. 2011. PMID: 21124082 Review.
Demonstration of the pathogenic potential of anti-neutrophil cytoplasm antibody (ANCA) has provided a rationale for antibody removal by PLEX in vasculitis therapy; however, other mechanisms may contribute to the therapeutic effect. ...PLEX remains a nonselective, ex …
Demonstration of the pathogenic potential of anti-neutrophil cytoplasm antibody (ANCA) has provided a rationale for antibody removal …
Long-term follow-up of patients with severe ANCA-associated vasculitis comparing plasma exchange to intravenous methylprednisolone treatment is unclear.
Walsh M, Casian A, Flossmann O, Westman K, Höglund P, Pusey C, Jayne DR; European Vasculitis Study Group (EUVAS). Walsh M, et al. Kidney Int. 2013 Aug;84(2):397-402. doi: 10.1038/ki.2013.131. Epub 2013 Apr 24. Kidney Int. 2013. PMID: 23615499 Clinical Trial.
Short-term results of a trial comparing plasma exchange (PLEX) to intravenous methylprednisolone (IV MeP) suggested PLEX improved renal recovery. ...A total of 137 patients with newly diagnosed AAV and a serum creatinine over 500 μmol/l or requiring dialysis …
Short-term results of a trial comparing plasma exchange (PLEX) to intravenous methylprednisolone (IV MeP) suggested PLEX improved ren …
Long-term outcome of severe alveolar haemorrhage in ANCA-associated vasculitis: a retrospective cohort study.
Hruskova Z, Casian AL, Konopasek P, Svobodova B, Frausova D, Lanska V, Tesar V, Jayne DR. Hruskova Z, et al. Scand J Rheumatol. 2013;42(3):211-4. doi: 10.3109/03009742.2012.754939. Epub 2013 Feb 4. Scand J Rheumatol. 2013. PMID: 23374071 Clinical Trial.
OBJECTIVES: Alveolar haemorrhage (AH) is a major cause of early death in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). There is a paucity of information regarding the outcomes of AAV patients presenting with severe AH. METHOD: A ret …
OBJECTIVES: Alveolar haemorrhage (AH) is a major cause of early death in anti-neutrophil cytoplasmic antibody (ANCA)-associated vascu …
Plasma exchange induces vitamin D deficiency.
Hiemstra TF, Casian A, Boraks P, Jayne DR, Schoenmakers I. Hiemstra TF, et al. QJM. 2014 Feb;107(2):123-30. doi: 10.1093/qjmed/hct208. Epub 2013 Oct 15. QJM. 2014. PMID: 24131546 Free PMC article.
CONCLUSION: Plasma exchange induced an acute reversible decrease in plasma 1,25-dihydroxyvitamin D, DBP, calcium and a sustained decrease in plasma 25-hydroxyvitamin D....
CONCLUSION: Plasma exchange induced an acute reversible decrease in plasma 1,25-dihydroxyvitamin D, DBP, calcium and a sustained decr …
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