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ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.
Trigueros-Motos L, van Capelleveen JC, Torta F, Castaño D, Zhang LH, Chai EC, Kang M, Dimova LG, Schimmel AWM, Tietjen I, Radomski C, Tan LJ, Thiam CH, Narayanaswamy P, Wu DH, Dorninger F, Yakala GK, Barhdadi A, Angeli V, Dubé MP, Berger J, Dallinga-Thie GM, Tietge UJF, Wenk MR, Hayden MR, Hovingh GK, Singaraja RR. Trigueros-Motos L, et al. Among authors: castano d. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2147-2155. doi: 10.1161/ATVBAHA.117.309574. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882873
Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice.
Liu Y, Castano D, Girolamo F, Trigueros-Motos L, Bae HG, Neo SP, Oh J, Narayanaswamy P, Torta F, Rye KA, Jo DG, Gunaratne J, Jung S, Virgintino D, Singaraja RR. Liu Y, et al. Among authors: castano d. J Lipid Res. 2022 Jan;63(1):100147. doi: 10.1016/j.jlr.2021.100147. Epub 2021 Nov 6. J Lipid Res. 2022. PMID: 34752805 Free PMC article.
Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice.
Chevre R, Trigueros-Motos L, Castaño D, Chua T, Corlianò M, Patankar JV, Sng L, Sim L, Juin TL, Carissimo G, Ng LFP, Yi CNJ, Eliathamby CC, Groen AK, Hayden MR, Singaraja RR. Chevre R, et al. Among authors: castano d. FASEB J. 2018 Jul;32(7):3792-3802. doi: 10.1096/fj.201701084RR. Epub 2018 Feb 26. FASEB J. 2018. PMID: 29481310
Taken together, our data demonstrate that Cyp8b1 inhibition is a viable therapeutic target of crucial interest for metabolic diseases, such as NAFLD.-Chevre, R., Trigueros-Motos, L., Castano, D., Chua, T., Corliano, M., Patankar, J. V., Sng, L., Sim, L., Juin, T. .. …
Taken together, our data demonstrate that Cyp8b1 inhibition is a viable therapeutic target of crucial interest for metabolic diseases, such …
Role of cardiotrophin-1 in obesity and insulin resistance.
Moreno-Aliaga MJ, Romero-Lozano MA, Castaño D, Prieto J, Bustos M. Moreno-Aliaga MJ, et al. Among authors: castano d. Adipocyte. 2012 Apr 1;1(2):112-115. doi: 10.4161/adip.19696. Adipocyte. 2012. PMID: 23700521 Free PMC article.
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals.
Lederer K, Bettini E, Parvathaneni K, Painter MM, Agarwal D, Lundgreen KA, Weirick M, Muralidharan K, Castaño D, Goel RR, Xu X, Drapeau EM, Gouma S, Ort JT, Awofolaju M, Greenplate AR, Le Coz C, Romberg N, Trofe-Clark J, Malat G, Jones L, Rosen M, Weiskopf D, Sette A, Besharatian B, Kaminiski M, Hensley SE, Bates P, Wherry EJ, Naji A, Bhoj V, Locci M. Lederer K, et al. Among authors: castano d. Cell. 2022 Mar 17;185(6):1008-1024.e15. doi: 10.1016/j.cell.2022.01.027. Epub 2022 Feb 2. Cell. 2022. PMID: 35202565 Free PMC article.
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