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15 results
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PIK3CA mutations in vascular malformations.
Castillo SD, Baselga E, Graupera M. Castillo SD, et al. Curr Opin Hematol. 2019 May;26(3):170-178. doi: 10.1097/MOH.0000000000000496. Curr Opin Hematol. 2019. PMID: 30855339 Free article. Review.
Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B. Castillo SD, et al. Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982. Sci Transl Med. 2016. PMID: 27030595 Free PMC article.
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Berenjeno IM, Piñeiro R, Castillo SD, Pearce W, McGranahan N, Dewhurst SM, Meniel V, Birkbak NJ, Lau E, Sansregret L, Morelli D, Kanu N, Srinivas S, Graupera M, Parker VER, Montgomery KG, Moniz LS, Scudamore CL, Phillips WA, Semple RK, Clarke A, Swanton C, Vanhaesebroeck B. Berenjeno IM, et al. Among authors: castillo sd. Nat Commun. 2017 Nov 24;8(1):1773. doi: 10.1038/s41467-017-02002-4. Nat Commun. 2017. PMID: 29170395 Free PMC article.
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting HG, Cutillas PR, Graupera M. Angulo-Urarte A, et al. Among authors: castillo sd. Nat Commun. 2018 Nov 16;9(1):4826. doi: 10.1038/s41467-018-07172-3. Nat Commun. 2018. PMID: 30446640 Free PMC article.
Determining the profiles and parameters for gene amplification testing of growth factor receptors in lung cancer.
Pros E, Lantuejoul S, Sanchez-Verde L, Castillo SD, Bonastre E, Suarez-Gauthier A, Conde E, Cigudosa JC, Lopez-Rios F, Torres-Lanzas J, Castellví J, Ramon y Cajal S, Brambilla E, Sanchez-Cespedes M. Pros E, et al. Among authors: castillo sd. Int J Cancer. 2013 Aug 15;133(4):898-907. doi: 10.1002/ijc.28090. Epub 2013 Mar 9. Int J Cancer. 2013. PMID: 23400671
15 results