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Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization.
Ferrini F, Perez-Sanchez J, Ferland S, Lorenzo LE, Godin AG, Plasencia-Fernandez I, Cottet M, Castonguay A, Wang F, Salio C, Doyon N, Merighi A, De Koninck Y. Ferrini F, et al. Among authors: castonguay a. Nat Commun. 2020 Aug 7;11(1):3935. doi: 10.1038/s41467-020-17824-y. Nat Commun. 2020. PMID: 32769979 Free PMC article.
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.
Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y. Ferrini F, et al. Among authors: castonguay a. Nat Neurosci. 2013 Feb;16(2):183-92. doi: 10.1038/nn.3295. Epub 2013 Jan 6. Nat Neurosci. 2013. PMID: 23292683 Free PMC article.
Chloride extrusion enhancers as novel therapeutics for neurological diseases.
Gagnon M, Bergeron MJ, Lavertu G, Castonguay A, Tripathy S, Bonin RP, Perez-Sanchez J, Boudreau D, Wang B, Dumas L, Valade I, Bachand K, Jacob-Wagner M, Tardif C, Kianicka I, Isenring P, Attardo G, Coull JA, De Koninck Y. Gagnon M, et al. Among authors: castonguay a. Nat Med. 2013 Nov;19(11):1524-8. doi: 10.1038/nm.3356. Epub 2013 Oct 6. Nat Med. 2013. PMID: 24097188 Free PMC article.
Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.
Richner M, Pallesen LT, Ulrichsen M, Poulsen ET, Holm TH, Login H, Castonguay A, Lorenzo LE, Gonçalves NP, Andersen OM, Lykke-Hartmann K, Enghild JJ, Rønn LCB, Malik IJ, De Koninck Y, Bjerrum OJ, Vægter CB, Nykjær A. Richner M, et al. Among authors: castonguay a. Sci Adv. 2019 Jun 19;5(6):eaav9946. doi: 10.1126/sciadv.aav9946. eCollection 2019 Jun. Sci Adv. 2019. PMID: 31223654 Free PMC article.
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.
Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. Taylor AM, et al. Among authors: castonguay a. Neuropsychopharmacology. 2016 Mar;41(4):949-59. doi: 10.1038/npp.2015.221. Epub 2015 Jul 23. Neuropsychopharmacology. 2016. PMID: 26202104 Free PMC article.
271 results