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IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression.
Wenzel SE, Balzar S, Ampleford E, Hawkins GA, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum S, Gaston B, Israel E, Teague WG, Curran-Everett D, Meyers DA, Bleecker ER. Wenzel SE, et al. Among authors: castro m. Am J Respir Crit Care Med. 2007 Mar 15;175(6):570-6. doi: 10.1164/rccm.200607-909OC. Epub 2006 Dec 14. Am J Respir Crit Care Med. 2007. PMID: 17170387 Free PMC article.
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: castro m. J Allergy Clin Immunol. 2007 Feb;119(2):405-13. doi: 10.1016/j.jaci.2006.11.639. J Allergy Clin Immunol. 2007. PMID: 17291857 Free PMC article.
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.
Planagumà A, Kazani S, Marigowda G, Haworth O, Mariani TJ, Israel E, Bleecker ER, Curran-Everett D, Erzurum SC, Calhoun WJ, Castro M, Chung KF, Gaston B, Jarjour NN, Busse WW, Wenzel SE, Levy BD. Planagumà A, et al. Among authors: castro m. Am J Respir Crit Care Med. 2008 Sep 15;178(6):574-82. doi: 10.1164/rccm.200801-061OC. Epub 2008 Jun 26. Am J Respir Crit Care Med. 2008. PMID: 18583575 Free PMC article.
Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology.
Aysola RS, Hoffman EA, Gierada D, Wenzel S, Cook-Granroth J, Tarsi J, Zheng J, Schechtman KB, Ramkumar TP, Cochran R, Xueping E, Christie C, Newell J, Fain S, Altes TA, Castro M. Aysola RS, et al. Among authors: castro m. Chest. 2008 Dec;134(6):1183-1191. doi: 10.1378/chest.07-2779. Epub 2008 Jul 18. Chest. 2008. PMID: 18641116 Free PMC article. Clinical Trial.
Randomized trial of the effect of drug presentation on asthma outcomes: the American Lung Association Asthma Clinical Research Centers.
Wise RA, Bartlett SJ, Brown ED, Castro M, Cohen R, Holbrook JT, Irvin CG, Rand CS, Sockrider MM, Sugar EA; American Lung Association Asthma Clinical Research Centers. Wise RA, et al. Among authors: castro m. J Allergy Clin Immunol. 2009 Sep;124(3):436-44, 444e1-8. doi: 10.1016/j.jaci.2009.05.041. Epub 2009 Jul 25. J Allergy Clin Immunol. 2009. PMID: 19632710 Free PMC article. Clinical Trial.
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.
Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: castro m. Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23. doi: 10.1164/rccm.200906-0896OC. Epub 2009 Nov 5. Am J Respir Crit Care Med. 2010. PMID: 19892860 Free PMC article.
5,120 results