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Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model.
Perlis RH, Iosifescu DV, Castro VM, Murphy SN, Gainer VS, Minnier J, Cai T, Goryachev S, Zeng Q, Gallagher PJ, Fava M, Weilburg JB, Churchill SE, Kohane IS, Smoller JW. Perlis RH, et al. Among authors: castro vm. Psychol Med. 2012 Jan;42(1):41-50. doi: 10.1017/S0033291711000997. Epub 2011 Jun 20. Psychol Med. 2012. PMID: 21682950 Free PMC article.
Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system.
Clements CC, Castro VM, Blumenthal SR, Rosenfield HR, Murphy SN, Fava M, Erb JL, Churchill SE, Kaimal AJ, Doyle AE, Robinson EB, Smoller JW, Kohane IS, Perlis RH. Clements CC, et al. Among authors: castro vm. Mol Psychiatry. 2015 Jun;20(6):727-34. doi: 10.1038/mp.2014.90. Epub 2014 Aug 26. Mol Psychiatry. 2015. PMID: 25155880 Free PMC article.
Validation of electronic health record phenotyping of bipolar disorder cases and controls.
Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW; International Cohort Collection for Bipolar Disorder Consortium. Castro VM, et al. Am J Psychiatry. 2015 Apr;172(4):363-72. doi: 10.1176/appi.ajp.2014.14030423. Epub 2014 Dec 12. Am J Psychiatry. 2015. PMID: 25827034 Free PMC article.
High-throughput multimodal automated phenotyping (MAP) with application to PheWAS.
Liao KP, Sun J, Cai TA, Link N, Hong C, Huang J, Huffman JE, Gronsbell J, Zhang Y, Ho YL, Castro V, Gainer V, Murphy SN, O'Donnell CJ, Gaziano JM, Cho K, Szolovits P, Kohane IS, Yu S, Cai T. Liao KP, et al. Among authors: castro v. J Am Med Inform Assoc. 2019 Nov 1;26(11):1255-1262. doi: 10.1093/jamia/ocz066. J Am Med Inform Assoc. 2019. PMID: 31613361 Free PMC article.
High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP).
Zhang Y, Cai T, Yu S, Cho K, Hong C, Sun J, Huang J, Ho YL, Ananthakrishnan AN, Xia Z, Shaw SY, Gainer V, Castro V, Link N, Honerlaw J, Huang S, Gagnon D, Karlson EW, Plenge RM, Szolovits P, Savova G, Churchill S, O'Donnell C, Murphy SN, Gaziano JM, Kohane I, Cai T, Liao KP. Zhang Y, et al. Among authors: castro v. Nat Protoc. 2019 Dec;14(12):3426-3444. doi: 10.1038/s41596-019-0227-6. Epub 2019 Nov 20. Nat Protoc. 2019. PMID: 31748751 Free PMC article.
Validation of an internationally derived patient severity phenotype to support COVID-19 analytics from electronic health record data.
Klann JG, Estiri H, Weber GM, Moal B, Avillach P, Hong C, Tan ALM, Beaulieu-Jones BK, Castro V, Maulhardt T, Geva A, Malovini A, South AM, Visweswaran S, Morris M, Samayamuthu MJ, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Xia Z, Hutch M, Luo Y, Kohane IS; Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (CONSORTIA AUTHOR); Brat GA, Murphy SN. Klann JG, et al. Among authors: castro v. J Am Med Inform Assoc. 2021 Jul 14;28(7):1411-1420. doi: 10.1093/jamia/ocab018. J Am Med Inform Assoc. 2021. PMID: 33566082 Free PMC article.
810 results