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Page 1
Pharmacological management of narcolepsy with and without cataplexy.
Kallweit U, Bassetti CL. Kallweit U, et al. Expert Opin Pharmacother. 2017 Jun;18(8):809-817. doi: 10.1080/14656566.2017.1323877. Epub 2017 May 17. Expert Opin Pharmacother. 2017. PMID: 28443381 Review.
Narcolepsy with cataplexy is most commonly caused by an immune-mediated process including genetic and environmental factors, resulting in the selective loss of hypocretin-producing neurons. ...First-line options include Modafinil/Armodafinil (for excessive daytime s …
Narcolepsy with cataplexy is most commonly caused by an immune-mediated process including genetic and environmental factors, r …
Circuit mechanisms of sleepiness and cataplexy in narcolepsy.
Pintwala S, Peever J. Pintwala S, et al. Curr Opin Neurobiol. 2017 Jun;44:50-58. doi: 10.1016/j.conb.2017.02.010. Epub 2017 Mar 23. Curr Opin Neurobiol. 2017. PMID: 28343142 Review.
Excessive daytime sleepiness and cataplexy are the major complaints in narcolepsy, and are associated with impaired quality of life. Although it is unclear how orexin loss causes sleepiness and cataplexy, animal models have been instrumental in identifying th …
Excessive daytime sleepiness and cataplexy are the major complaints in narcolepsy, and are associated with impaired quality of …
Type 1 narcolepsy without cataplexy and treatment progress: a case report.
Huang R, Ding X, Cao X, Chen L, Chai W, Chen X. Huang R, et al. Ann Palliat Med. 2021 Mar;10(3):3491-3494. doi: 10.21037/apm-21-220. Ann Palliat Med. 2021. PMID: 33849131 Free article. Review.
Narcolepsy is a sleep disorder with the main manifestations of excessive daytime sleepiness, cataplexy, sleep paralysis, sleep hallucinations, and nighttime sleep disturbance. ...In the present study, we report the first case of narcolepsy diagnosed at the di …
Narcolepsy is a sleep disorder with the main manifestations of excessive daytime sleepiness, cataplexy, sleep paralysis, sleep …
Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system.
Nishino S, Kanbayashi T. Nishino S, et al. Sleep Med Rev. 2005 Aug;9(4):269-310. doi: 10.1016/j.smrv.2005.03.004. Sleep Med Rev. 2005. PMID: 16006155 Review.
The symptoms of narcolepsy can also occur during the course of other neurological conditions (i.e. symptomatic narcolepsy). ...It appears that further studies of the involvement of the hypocretin system in symptomatic narcolepsy and EDS are helpful to underst …
The symptoms of narcolepsy can also occur during the course of other neurological conditions (i.e. symptomatic narcolepsy). .. …
Pharmacological management of narcolepsy and cataplexy in pediatric patients.
Lecendreux M. Lecendreux M. Paediatr Drugs. 2014 Oct;16(5):363-72. doi: 10.1007/s40272-014-0083-3. Paediatr Drugs. 2014. PMID: 25074415 Review.
Narcolepsy is a neurological disorder frequently occurring from childhood and persisting through adolescence and adulthood. Individuals suffering from narcolepsy exhibit excessive daytime somnolence, sleep attacks, cataplexy, dysomnia, metabolic perturbations …
Narcolepsy is a neurological disorder frequently occurring from childhood and persisting through adolescence and adulthood. Individua …
Narcolepsy.
Barateau L, Pizza F, Plazzi G, Dauvilliers Y. Barateau L, et al. J Sleep Res. 2022 Aug;31(4):e13631. doi: 10.1111/jsr.13631. Epub 2022 May 27. J Sleep Res. 2022. PMID: 35624073 Review.
This article addresses the clinical presentation, diagnosis, pathophysiology and management of narcolepsy type 1 and 2, with a focus on recent findings. A low level of hypocretin-1/orexin-A in the cerebrospinal fluid is sufficient to diagnose narcolepsy type 1, bein …
This article addresses the clinical presentation, diagnosis, pathophysiology and management of narcolepsy type 1 and 2, with a focus …
Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy.
Liblau RS, Vassalli A, Seifinejad A, Tafti M. Liblau RS, et al. Lancet Neurol. 2015 Mar;14(3):318-28. doi: 10.1016/S1474-4422(14)70218-2. Epub 2015 Feb 16. Lancet Neurol. 2015. PMID: 25728441 Review.
The discovery of hypocretins (orexins) and their causal implication in narcolepsy is the most important advance in sleep research and sleep medicine since the discovery of rapid eye movement sleep. Narcolepsy with cataplexy is caused by hypocretin deficiency …
The discovery of hypocretins (orexins) and their causal implication in narcolepsy is the most important advance in sleep research and …
Narcolepsies, update in 2023.
Barateau L, Pizza F, Chenini S, Peter-Derex L, Dauvilliers Y. Barateau L, et al. Rev Neurol (Paris). 2023 Oct;179(7):727-740. doi: 10.1016/j.neurol.2023.08.001. Epub 2023 Aug 25. Rev Neurol (Paris). 2023. PMID: 37634997 Review.
Narcolepsy type 1 (NT1) and type 2 (NT2), also known as narcolepsy with and without cataplexy, are sleep disorders that benefited from major scientific advances over the last two decades. ...Orexin-deficiency is responsible for the main NT1 symptoms: sleepine …
Narcolepsy type 1 (NT1) and type 2 (NT2), also known as narcolepsy with and without cataplexy, are sleep disorders that …
Cataplexy associated with narcolepsy: epidemiology, pathophysiology and management.
Thorpy MJ. Thorpy MJ. CNS Drugs. 2006;20(1):43-50. doi: 10.2165/00023210-200620010-00004. CNS Drugs. 2006. PMID: 16396523 Review.
The onset of narcolepsy typically occurs in early adulthood and may consist of a variety of symptoms; however, cataplexy (an abrupt, bilateral loss of skeletal muscle tone) is most specific to narcolepsy. ...The recent availability of sodium oxybate (the firs …
The onset of narcolepsy typically occurs in early adulthood and may consist of a variety of symptoms; however, cataplexy (an a …
Assessing sleepiness and cataplexy in children and adolescents with narcolepsy: a review of current patient-reported measures.
Benmedjahed K, Wang YG, Lambert J, Evans C, Hwang S, Black J, Johns MW. Benmedjahed K, et al. Sleep Med. 2017 Apr;32:143-149. doi: 10.1016/j.sleep.2016.12.020. Epub 2017 Jan 20. Sleep Med. 2017. PMID: 28366326 Free article. Review.
OBJECTIVE: The objective of this study was to review patient-reported outcome measures assessing excessive daytime sleepiness (EDS) or cataplexy in children or adolescents to determine their usefulness and limitations in pediatric narcolepsy assessment. ...CONCLUSIO …
OBJECTIVE: The objective of this study was to review patient-reported outcome measures assessing excessive daytime sleepiness (EDS) or ca …
7,314 results