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Custom zinc-finger nucleases for use in human cells.
Alwin S, Gere MB, Guhl E, Effertz K, Barbas CF 3rd, Segal DJ, Weitzman MD, Cathomen T. Alwin S, et al. Among authors: cathomen t. Mol Ther. 2005 Oct;12(4):610-7. doi: 10.1016/j.ymthe.2005.06.094. Mol Ther. 2005. PMID: 16039907
Unexpected failure rates for modular assembly of engineered zinc fingers.
Ramirez CL, Foley JE, Wright DA, Müller-Lerch F, Rahman SH, Cornu TI, Winfrey RJ, Sander JD, Fu F, Townsend JA, Cathomen T, Voytas DF, Joung JK. Ramirez CL, et al. Among authors: cathomen t. Nat Methods. 2008 May;5(5):374-5. doi: 10.1038/nmeth0508-374. Nat Methods. 2008. PMID: 18446154 Free PMC article. No abstract available.
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.
Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB Jr, Cathomen T, Voytas DF, Joung JK. Maeder ML, et al. Among authors: cathomen t. Mol Cell. 2008 Jul 25;31(2):294-301. doi: 10.1016/j.molcel.2008.06.016. Mol Cell. 2008. PMID: 18657511 Free PMC article.
125 results