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Carnosine protects stimulus-secretion coupling through prevention of protein carbonyl adduction events in cells under metabolic stress.
Lavilla CJ, Billacura MP, Hanna K, Boocock DJ, Coveney C, Miles AK, Foulds GA, Murphy A, Tan A, Jackisch L, Sayers SR, Caton PW, Doig CL, McTernan PG, Colombo SL, Sale C, Turner MD. Lavilla CJ, et al. Among authors: caton pw. Free Radic Biol Med. 2021 Nov 1;175:65-79. doi: 10.1016/j.freeradbiomed.2021.08.233. Epub 2021 Aug 27. Free Radic Biol Med. 2021. PMID: 34455039
Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes.
Sayers SR, Beavil RL, Fine NHF, Huang GC, Choudhary P, Pacholarz KJ, Barran PE, Butterworth S, Mills CE, Cruickshank JK, Silvestre MP, Poppitt SD, McGill AT, Lavery GG, Hodson DJ, Caton PW. Sayers SR, et al. Among authors: caton pw. Diabetologia. 2020 Feb;63(2):313-323. doi: 10.1007/s00125-019-05029-y. Epub 2019 Nov 15. Diabetologia. 2020. PMID: 31732790 Free PMC article.
31 results