Caunt CJ - Search Results

1

MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.

Caunt CJ, Sale MJ, Smith PD, Cook SJ. Caunt CJ, et al. Nat Rev Cancer. 2015 Oct;15(10):577-92. doi: 10.1038/nrc4000. Nat Rev Cancer. 2015. PMID: 26399658 Review.

2

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling.

Kidger AM, Rushworth LK, Stellzig J, Davidson J, Bryant CJ, Bayley C, Caddye E, Rogers T, Keyse SM, Caunt CJ. Kidger AM, et al. Among authors: caunt cj. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E317-E326. doi: 10.1073/pnas.1614684114. Epub 2017 Jan 4. Proc Natl Acad Sci U S A. 2017. PMID: 28053233 Free PMC article.

3

Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe.

Sipthorp J, Lebraud H, Gilley R, Kidger AM, Okkenhaug H, Saba-El-Leil M, Meloche S, Caunt CJ, Cook SJ, Heightman TD. Sipthorp J, et al. Among authors: caunt cj. Bioconjug Chem. 2017 Jun 21;28(6):1677-1683. doi: 10.1021/acs.bioconjchem.7b00152. Epub 2017 May 12. Bioconjug Chem. 2017. PMID: 28449575 Free article.

4

Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK.

Hey F, Andreadi C, Noble C, Patel B, Jin H, Kamata T, Straatman K, Luo J, Balmanno K, Jones DTW, Collins VP, Cook SJ, Caunt CJ, Pritchard C. Hey F, et al. Among authors: caunt cj. Heliyon. 2018 Dec 20;4(12):e01065. doi: 10.1016/j.heliyon.2018.e01065. eCollection 2018 Dec. Heliyon. 2018. PMID: 30603699 Free PMC article.

5

Visualizing and Quantitating the Spatiotemporal Regulation of Ras/ERK Signaling by Dual-Specificity Mitogen-Activated Protein Phosphatases (MKPs).

Caunt CJ, Kidger AM, Keyse SM. Caunt CJ, et al. Methods Mol Biol. 2016;1447:197-215. doi: 10.1007/978-1-4939-3746-2_12. Methods Mol Biol. 2016. PMID: 27514808

6

Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G. Bailey CP, et al. Among authors: caunt cj. Br J Pharmacol. 2009 Sep;158(1):157-64. doi: 10.1111/j.1476-5381.2009.00140.x. Epub 2009 Mar 20. Br J Pharmacol. 2009. PMID: 19309357 Free PMC article.

7

Information Transfer in Gonadotropin-releasing Hormone (GnRH) Signaling: EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK)-MEDIATED FEEDBACK LOOPS CONTROL HORMONE SENSING.

Garner KL, Perrett RM, Voliotis M, Bowsher C, Pope GR, Pham T, Caunt CJ, Tsaneva-Atanasova K, McArdle CA. Garner KL, et al. Among authors: caunt cj. J Biol Chem. 2016 Jan 29;291(5):2246-59. doi: 10.1074/jbc.M115.686964. Epub 2015 Dec 7. J Biol Chem. 2016. PMID: 26644469 Free PMC article.

8

Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.

Rushworth LK, Kidger AM, Delavaine L, Stewart G, van Schelven S, Davidson J, Bryant CJ, Caddye E, East P, Caunt CJ, Keyse SM. Rushworth LK, et al. Among authors: caunt cj. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18267-72. doi: 10.1073/pnas.1420159112. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489104 Free PMC article.

9

Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.

Caunt CJ, Keyse SM. Caunt CJ, et al. FEBS J. 2013 Jan;280(2):489-504. doi: 10.1111/j.1742-4658.2012.08716.x. Epub 2012 Aug 28. FEBS J. 2013. PMID: 22812510 Free PMC article. Review.

10

ERK phosphorylation and nuclear accumulation: insights from single-cell imaging.

Caunt CJ, McArdle CA. Caunt CJ, et al. Biochem Soc Trans. 2012 Feb;40(1):224-9. doi: 10.1042/BST20110662. Biochem Soc Trans. 2012. PMID: 22260695

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