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CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo.
Bos FL, Caunt M, Peterson-Maduro J, Planas-Paz L, Kowalski J, Karpanen T, van Impel A, Tong R, Ernst JA, Korving J, van Es JH, Lammert E, Duckers HJ, Schulte-Merker S. Bos FL, et al. Among authors: caunt m. Circ Res. 2011 Aug 19;109(5):486-91. doi: 10.1161/CIRCRESAHA.111.250738. Epub 2011 Jul 21. Circ Res. 2011. PMID: 21778431
Blocking neuropilin-2 function inhibits tumor cell metastasis.
Caunt M, Mak J, Liang WC, Stawicki S, Pan Q, Tong RK, Kowalski J, Ho C, Reslan HB, Ross J, Berry L, Kasman I, Zlot C, Cheng Z, Le Couter J, Filvaroff EH, Plowman G, Peale F, French D, Carano R, Koch AW, Wu Y, Watts RJ, Tessier-Lavigne M, Bagri A. Caunt M, et al. Cancer Cell. 2008 Apr;13(4):331-42. doi: 10.1016/j.ccr.2008.01.029. Cancer Cell. 2008. PMID: 18394556 Free article.
Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.
Sampath D, Oeh J, Wyatt SK, Cao TC, Koeppen H, Eastham-Anderson J, Robillard L, Ho CC, Ross J, Zhuang G, Reslan HB, Vitorino P, Barck KH, Ungersma SE, Vernes JM, Caunt M, Van Bruggen N, Ye W, Vijapurkar U, Meng YJ, Ferrara N, Friedman LS, Carano RA. Sampath D, et al. Among authors: caunt m. Neoplasia. 2013 Jul;15(7):694-711. doi: 10.1593/neo.13470. Neoplasia. 2013. PMID: 23814482 Free PMC article.
Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3.
Xu Y, Yuan L, Mak J, Pardanaud L, Caunt M, Kasman I, Larrivée B, Del Toro R, Suchting S, Medvinsky A, Silva J, Yang J, Thomas JL, Koch AW, Alitalo K, Eichmann A, Bagri A. Xu Y, et al. Among authors: caunt m. J Cell Biol. 2010 Jan 11;188(1):115-30. doi: 10.1083/jcb.200903137. J Cell Biol. 2010. PMID: 20065093 Free PMC article.
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