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Mitochondrial processing peptidases.
Gakh O, Cavadini P, Isaya G. Gakh O, et al. Among authors: cavadini p. Biochim Biophys Acta. 2002 Sep 2;1592(1):63-77. doi: 10.1016/s0167-4889(02)00265-3. Biochim Biophys Acta. 2002. PMID: 12191769 Review.
The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin.
Zanella I, Derosas M, Corrado M, Cocco E, Cavadini P, Biasiotto G, Poli M, Verardi R, Arosio P. Zanella I, et al. Among authors: cavadini p. Biochim Biophys Acta. 2008 Feb;1782(2):90-8. doi: 10.1016/j.bbadis.2007.11.006. Epub 2007 Dec 5. Biochim Biophys Acta. 2008. PMID: 18160053
Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia.
Cavadini P, O'Neill HA, Benada O, Isaya G. Cavadini P, et al. Hum Mol Genet. 2002 Feb 1;11(3):217-27. doi: 10.1093/hmg/11.3.217. Hum Mol Genet. 2002. PMID: 11823441
Protein import and processing reconstituted with isolated rat liver mitochondria and recombinant mitochondrial processing peptidase.
Cavadini P, Gakh O, Isaya G. Cavadini P, et al. Methods. 2002 Apr;26(4):298-306. doi: 10.1016/S1046-2023(02)00035-X. Methods. 2002. PMID: 12054920
Human frataxin maintains mitochondrial iron homeostasis in Saccharomyces cerevisiae.
Cavadini P, Gellera C, Patel PI, Isaya G. Cavadini P, et al. Hum Mol Genet. 2000 Oct 12;9(17):2523-30. doi: 10.1093/hmg/9.17.2523. Hum Mol Genet. 2000. PMID: 11030757
Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase.
Branda SS, Cavadini P, Adamec J, Kalousek F, Taroni F, Isaya G. Branda SS, et al. Among authors: cavadini p. J Biol Chem. 1999 Aug 6;274(32):22763-9. doi: 10.1074/jbc.274.32.22763. J Biol Chem. 1999. PMID: 10428860
Two-step processing of human frataxin by mitochondrial processing peptidase. Precursor and intermediate forms are cleaved at different rates.
Cavadini P, Adamec J, Taroni F, Gakh O, Isaya G. Cavadini P, et al. J Biol Chem. 2000 Dec 29;275(52):41469-75. doi: 10.1074/jbc.M006539200. J Biol Chem. 2000. PMID: 11020385
We showed previously that maturation of the human frataxin precursor (p-fxn) involves two cleavages by the mitochondrial processing peptidase (MPP). ...Recombinant rat and yeast MPP catalyze the p --> i step 4 and 40 times faster, respectively, than the i --> …
We showed previously that maturation of the human frataxin precursor (p-fxn) involves two cleavages by the mitochondrial processing p …
Ferritins: a family of molecules for iron storage, antioxidation and more.
Arosio P, Ingrassia R, Cavadini P. Arosio P, et al. Among authors: cavadini p. Biochim Biophys Acta. 2009 Jul;1790(7):589-99. doi: 10.1016/j.bbagen.2008.09.004. Epub 2008 Sep 26. Biochim Biophys Acta. 2009. PMID: 18929623 Review.
Cloning, sequencing and regulation of a cDNA encoding a small heat-shock protein from Schizosaccharomyces pombe.
Orlandi I, Cavadini P, Popolo L, Vai M. Orlandi I, et al. Among authors: cavadini p. Biochim Biophys Acta. 1996 Jun 7;1307(2):129-31. doi: 10.1016/0167-4781(96)00045-0. Biochim Biophys Acta. 1996. PMID: 8679693
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis.
Wong A, Yang J, Cavadini P, Gellera C, Lonnerdal B, Taroni F, Cortopassi G. Wong A, et al. Among authors: cavadini p. Hum Mol Genet. 1999 Mar;8(3):425-30. doi: 10.1093/hmg/8.3.425. Hum Mol Genet. 1999. PMID: 9949201
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