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The purification of early-pregnancy factor to homogeneity from human platelets and identification as chaperonin 10.
Cavanagh AC, Morton H. Cavanagh AC, et al. Eur J Biochem. 1994 Jun 1;222(2):551-60. doi: 10.1111/j.1432-1033.1994.tb18897.x. Eur J Biochem. 1994. PMID: 7912672
Investigation of the immunocompetent cells that bind early pregnancy factor and preliminary studies of the early pregnancy factor target molecule.
Athanasas-Platsis S, Somodevilla-Torres MJ, Morton H, Cavanagh AC. Athanasas-Platsis S, et al. Among authors: cavanagh ac. Immunol Cell Biol. 2004 Aug;82(4):361-9. doi: 10.1111/j.0818-9641.2004.01260.x. Immunol Cell Biol. 2004. PMID: 15283845
Purification and characterisation of functional early pregnancy factor expressed in Sf9 insect cells and in Escherichia coli.
Somodevilla-Torres MJ, Morton H, Zhang B, Reid S, Cavanagh AC. Somodevilla-Torres MJ, et al. Among authors: cavanagh ac. Protein Expr Purif. 2003 Dec;32(2):276-87. doi: 10.1016/j.pep.2003.08.011. Protein Expr Purif. 2003. PMID: 14965774
Early pregnancy factor treatment suppresses the inflammatory response and adhesion molecule expression in the spinal cord of SJL/J mice with experimental autoimmune encephalomyelitis and the delayed-type hypersensitivity reaction to trinitrochlorobenzene in normal BALB/c mice.
Zhang B, Walsh MD, Nguyen KB, Hillyard NC, Cavanagh AC, McCombe PA, Morton H. Zhang B, et al. Among authors: cavanagh ac. J Neurol Sci. 2003 Aug 15;212(1-2):37-46. doi: 10.1016/s0022-510x(03)00103-5. J Neurol Sci. 2003. PMID: 12809997
Early pregnancy factor suppresses the infiltration of lymphocytes and macrophages in the spinal cord of rats during experimental autoimmune encephalomyelitis but has no effect on apoptosis.
Athanasas-Platsis S, Zhang B, Hillyard NC, Cavanagh AC, Csurhes PA, Morton H, McCombe PA. Athanasas-Platsis S, et al. Among authors: cavanagh ac. J Neurol Sci. 2003 Oct 15;214(1-2):27-36. doi: 10.1016/s0022-510x(03)00170-9. J Neurol Sci. 2003. PMID: 12972385
A protective effect of early pregnancy factor on experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein.
Harness J, Cavanagh A, Morton H, McCombe P. Harness J, et al. Among authors: cavanagh a. J Neurol Sci. 2003 Dec 15;216(1):33-41. doi: 10.1016/s0022-510x(03)00212-0. J Neurol Sci. 2003. PMID: 14607300
Isolation of antibodies which neutralise the activity of early pregnancy factor.
Hammond F, Cavanagh A, Morton H, Hillyard N, Papaioannou A, Clark M, Wanigesekera D, Swanton M, Ward R. Hammond F, et al. Among authors: cavanagh a. J Immunol Methods. 2000 Oct 20;244(1-2):175-84. doi: 10.1016/s0022-1759(00)00235-0. J Immunol Methods. 2000. PMID: 11033030
Genetically-restricted effector molecules released by human lymphocytes in response to early pregnancy factor.
Rolfe B, Quinn K, Athanasas S, Cavanagh A, Morton H. Rolfe B, et al. Among authors: cavanagh a. Immunol Cell Biol. 1989 Jun;67 ( Pt 3):205-8. doi: 10.1038/icb.1989.31. Immunol Cell Biol. 1989. PMID: 2793206
Modified rosette inhibition test with mouse lymphocytes for detection of early pregnancy factor in human pregnancy serum.
Rolfe B, Cavanagh A, Forde C, Bastin F, Chen C, Morton H. Rolfe B, et al. Among authors: cavanagh a. J Immunol Methods. 1984 May 11;70(1):1-11. doi: 10.1016/0022-1759(84)90383-1. J Immunol Methods. 1984. PMID: 6715892
Preparation and characterization of polyclonal antibodies against human chaperonin 10.
Somodevilla-Torres MJ, Hillyard NC, Morton H, Alewood D, Halliday JA, Alewood PF, Vesey DA, Walsh MD, Cavanagh AC. Somodevilla-Torres MJ, et al. Among authors: cavanagh ac. Cell Stress Chaperones. 2000 Jan;5(1):14-20. doi: 10.1043/1355-8145(2000)005<0014:PACOPA>2.0.CO;2. Cell Stress Chaperones. 2000. PMID: 10701835 Free PMC article.
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