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PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.
Wick W, Furnari FB, Naumann U, Cavenee WK, Weller M. Wick W, et al. Among authors: cavenee wk. Oncogene. 1999 Jul 8;18(27):3936-43. doi: 10.1038/sj.onc.1202774. Oncogene. 1999. PMID: 10435616
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells.
Furnari FB, Huang HJ, Cavenee WK. Furnari FB, et al. Among authors: cavenee wk. Cancer Res. 1998 Nov 15;58(22):5002-8. Cancer Res. 1998. PMID: 9823298
Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma.
Arap W, Knudsen ES, Wang JY, Cavenee WK, Huang HJ. Arap W, et al. Among authors: cavenee wk. Oncogene. 1997 Feb 6;14(5):603-9. doi: 10.1038/sj.onc.1200870. Oncogene. 1997. PMID: 9053859
In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma.
Robertson GP, Furnari FB, Miele ME, Glendening MJ, Welch DR, Fountain JW, Lugo TG, Huang HJ, Cavenee WK. Robertson GP, et al. Among authors: cavenee wk. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9418-23. doi: 10.1073/pnas.95.16.9418. Proc Natl Acad Sci U S A. 1998. PMID: 9689095 Free PMC article.
The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death.
Knudsen KE, Weber E, Arden KC, Cavenee WK, Feramisco JR, Knudsen ES. Knudsen KE, et al. Among authors: cavenee wk. Oncogene. 1999 Sep 16;18(37):5239-45. doi: 10.1038/sj.onc.1202910. Oncogene. 1999. PMID: 10498874
Functional analysis of wild-type and malignant glioma derived CDKN2Abeta alleles: evidence for an RB-independent growth suppressive pathway.
Arap W, Knudsen E, Sewell DA, Sidransky D, Wang JY, Huang HJ, Cavenee WK. Arap W, et al. Among authors: cavenee wk. Oncogene. 1997 Oct 23;15(17):2013-20. doi: 10.1038/sj.onc.1201389. Oncogene. 1997. PMID: 9366518
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain.
Furnari FB, Lin H, Huang HS, Cavenee WK. Furnari FB, et al. Among authors: cavenee wk. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12479-84. doi: 10.1073/pnas.94.23.12479. Proc Natl Acad Sci U S A. 1997. PMID: 9356475 Free PMC article.
Replacement of the p16/CDKN2 gene suppresses human glioma cell growth.
Arap W, Nishikawa R, Furnari FB, Cavenee WK, Huang HJ. Arap W, et al. Among authors: cavenee wk. Cancer Res. 1995 Mar 15;55(6):1351-4. Cancer Res. 1995. PMID: 7882335
FHL2 interacts with EGFR to promote glioblastoma growth.
Sun L, Yu S, Xu H, Zheng Y, Lin J, Wu M, Wang J, Wang A, Lan Q, Furnari F, Cavenee W, Purow B, Li M. Sun L, et al. Oncogene. 2018 Mar;37(10):1386-1398. doi: 10.1038/s41388-017-0068-0. Epub 2018 Jan 11. Oncogene. 2018. PMID: 29321665
PTEN: a novel anti-oncogenic function independent of phosphatase activity.
Okumura K, Zhao M, DePinho RA, Furnari FB, Cavenee WK. Okumura K, et al. Among authors: cavenee wk. Cell Cycle. 2005 Apr;4(4):540-2. doi: 10.4161/cc.4.4.1614. Epub 2005 Apr 21. Cell Cycle. 2005. PMID: 15753657 Review.
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