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Page 1
Cloning and characterization of the human and mouse PDE7B, a novel cAMP-specific cyclic nucleotide phosphodiesterase.
Gardner C, Robas N, Cawkill D, Fidock M. Gardner C, et al. Among authors: cawkill d. Biochem Biophys Res Commun. 2000 May 27;272(1):186-92. doi: 10.1006/bbrc.2000.2743. Biochem Biophys Res Commun. 2000. PMID: 10872825
Use of reduced temperature cell pausing to enhance flexibility of cell-based assays.
Wise H, Abel PW, Cawkill D. Wise H, et al. Among authors: cawkill d. J Biomol Screen. 2009 Jul;14(6):716-22. doi: 10.1177/1087057109335748. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470715
Evolution of cell-based reagent provision.
Cawkill D, Eaglestone SS. Cawkill D, et al. Drug Discov Today. 2007 Oct;12(19-20):820-5. doi: 10.1016/j.drudis.2007.08.014. Epub 2007 Sep 27. Drug Discov Today. 2007. PMID: 17933682 Review.
High-throughput lead finding and optimisation for GPCR targets.
Sewing A, Cawkill D. Sewing A, et al. Among authors: cawkill d. Ernst Schering Found Symp Proc. 2006;(2):249-67. doi: 10.1007/2789_2006_012. Ernst Schering Found Symp Proc. 2006. PMID: 17703586 Review.
Identification of Positive Allosteric Modulators of Glycine Receptors from a High-Throughput Screen Using a Fluorescent Membrane Potential Assay.
Stead C, Brown A, Adams C, Nickolls SJ, Young G, Kammonen J, Pryde D, Cawkill D. Stead C, et al. Among authors: cawkill d. J Biomol Screen. 2016 Dec;21(10):1042-1053. doi: 10.1177/1087057116657779. Epub 2016 Jul 11. J Biomol Screen. 2016. PMID: 27412533
Biased ligand quantification in drug discovery: from theory to high throughput screening to identify new biased μ opioid receptor agonists.
Winpenny D, Clark M, Cawkill D. Winpenny D, et al. Among authors: cawkill d. Br J Pharmacol. 2016 Apr;173(8):1393-403. doi: 10.1111/bph.13441. Epub 2016 Mar 1. Br J Pharmacol. 2016. PMID: 26791140 Free PMC article.
Plate-Based Phenotypic Screening for Pain Using Human iPSC-Derived Sensory Neurons.
Stacey P, Wassermann AM, Kammonen L, Impey E, Wilbrey A, Cawkill D. Stacey P, et al. Among authors: cawkill d. SLAS Discov. 2018 Jul;23(6):585-596. doi: 10.1177/2472555218764678. Epub 2018 Mar 16. SLAS Discov. 2018. PMID: 29547351
Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: cawkill d. Nat Commun. 2020 Apr 16;11(1):1929. doi: 10.1038/s41467-020-15945-y. Nat Commun. 2020. PMID: 32300106 Free PMC article.
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: cawkill d. Nat Commun. 2019 Sep 9;10(1):4075. doi: 10.1038/s41467-019-11875-6. Nat Commun. 2019. PMID: 31501422 Free PMC article.
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