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TNF-alpha and adipocyte biology.

Cawthorn WP, Sethi JK. Cawthorn WP, et al. FEBS Lett. 2008 Jan 9;582(1):117-31. doi: 10.1016/j.febslet.2007.11.051. Epub 2007 Nov 26. FEBS Lett. 2008. PMID: 18037376 Free PMC article. Review.

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Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network.

Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK. Lagathu C, et al. Among authors: cawthorn wp. Diabetes. 2009 Mar;58(3):609-19. doi: 10.2337/db08-1180. Epub 2008 Dec 10. Diabetes. 2009. PMID: 19073771 Free PMC article.

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Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation.

Patel MN, Bernard WG, Milev NB, Cawthorn WP, Figg N, Hart D, Prieur X, Virtue S, Hegyi K, Bonnafous S, Bailly-Maitre B, Chu Y, Griffin JL, Mallat Z, Considine RV, Tran A, Gual P, Takeuchi O, Akira S, Vidal-Puig A, Bennett MR, Sethi JK. Patel MN, et al. Among authors: cawthorn wp. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):506-11. doi: 10.1073/pnas.1414536112. Epub 2014 Dec 24. Proc Natl Acad Sci U S A. 2015. PMID: 25540417 Free PMC article.

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Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway.

Cawthorn WP, Heyd F, Hegyi K, Sethi JK. Cawthorn WP, et al. Cell Death Differ. 2007 Jul;14(7):1361-73. doi: 10.1038/sj.cdd.4402127. Epub 2007 Apr 20. Cell Death Differ. 2007. PMID: 17464333 Free PMC article.

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The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation.

Boyle KB, Hadaschik D, Virtue S, Cawthorn WP, Ridley SH, O'Rahilly S, Siddle K. Boyle KB, et al. Among authors: cawthorn wp. Cell Death Differ. 2009 May;16(5):782-9. doi: 10.1038/cdd.2009.11. Epub 2009 Feb 20. Cell Death Differ. 2009. PMID: 19229250 Free PMC article.

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The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis.

Christodoulides C, Laudes M, Cawthorn WP, Schinner S, Soos M, O'Rahilly S, Sethi JK, Vidal-Puig A. Christodoulides C, et al. Among authors: cawthorn wp. J Cell Sci. 2006 Jun 15;119(Pt 12):2613-2620. doi: 10.1242/jcs.02975. J Cell Sci. 2006. PMID: 16763196 Free PMC article.

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IGF-binding protein-2 protects against the development of obesity and insulin resistance.

Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA. Wheatcroft SB, et al. Among authors: cawthorn wp. Diabetes. 2007 Feb;56(2):285-94. doi: 10.2337/db06-0436. Diabetes. 2007. PMID: 17259371 Free PMC article.

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Sweet taste receptor deficient mice have decreased adiposity and increased bone mass.

Simon BR, Learman BS, Parlee SD, Scheller EL, Mori H, Cawthorn WP, Ning X, Krishnan V, Ma YL, Tyrberg B, MacDougald OA. Simon BR, et al. Among authors: cawthorn wp. PLoS One. 2014 Jan 22;9(1):e86454. doi: 10.1371/journal.pone.0086454. eCollection 2014. PLoS One. 2014. PMID: 24466105 Free PMC article.

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Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease.

Mcilroy GD, Suchacki K, Roelofs AJ, Yang W, Fu Y, Bai B, Wallace RJ, De Bari C, Cawthorn WP, Han W, Delibegović M, Rochford JJ. Mcilroy GD, et al. Among authors: cawthorn wp. Mol Metab. 2018 Apr;10:55-65. doi: 10.1016/j.molmet.2018.01.019. Epub 2018 Jan 31. Mol Metab. 2018. PMID: 29459250 Free PMC article.

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Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues.

Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, MacDougald OA. Scheller EL, et al. Among authors: cawthorn wp. Nat Commun. 2015 Aug 6;6:7808. doi: 10.1038/ncomms8808. Nat Commun. 2015. PMID: 26245716 Free PMC article.

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