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Page 1
[Cefadroxil].
Fujimori I. Fujimori I. Jpn J Antibiot. 1982 Dec;35(12):2736-47. Jpn J Antibiot. 1982. PMID: 6763635 Review. Japanese. No abstract available.
Cefadroxil and cephalexin pharmacokinetics and pharmacodynamics in children with musculoskeletal infections.
Haynes AS, Wei Z, Anderson P, Scheetz MH, Parker SK, Fish DN. Haynes AS, et al. Antimicrob Agents Chemother. 2024 May 2;68(5):e0018224. doi: 10.1128/aac.00182-24. Epub 2024 Apr 10. Antimicrob Agents Chemother. 2024. PMID: 38597672 Free PMC article.
PK parameters were notable for cefadroxil's longer half-life (1.61 h) than cephalexin's (1.10 h). For pediatric weight bands, our primary PD target was achieved by cephalexin 25 mg/kg/dose, maximum 750 mg/dose, administered three times daily and cefadroxil 40 mg/kg/ …
PK parameters were notable for cefadroxil's longer half-life (1.61 h) than cephalexin's (1.10 h). For pediatric weight bands, our pri …
Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine.
Tanrisever B, Santella PJ. Tanrisever B, et al. Drugs. 1986;32 Suppl 3:1-16. doi: 10.2165/00003495-198600323-00003. Drugs. 1986. PMID: 3542485 Review.
Not only does cefadroxil exhibit a longer serum half-life, and thus a prolonged duration of activity, but it is virtually unaffected by simultaneous food intake. The concentrations of cefadroxil attained in body tissues and fluids are also higher and more sustained …
Not only does cefadroxil exhibit a longer serum half-life, and thus a prolonged duration of activity, but it is virtually unaffected …
Characteristics, Properties and Analytical Methods of Cefadroxil: A Review.
de Marco BA, Salgado HR. de Marco BA, et al. Crit Rev Anal Chem. 2017 Mar 4;47(2):93-98. doi: 10.1080/10408347.2016.1219649. Epub 2016 Aug 5. Crit Rev Anal Chem. 2017. PMID: 27494757 Review.
Infections are the second leading cause of mortality worldwide and there are many reasons justifying the need for further studies of antimicrobial agents. Cefadroxil is a drug that has bactericidal activity and broad spectrum of action. Quantitative analyzes about cefad …
Infections are the second leading cause of mortality worldwide and there are many reasons justifying the need for further studies of antimic …
Cefadroxil Comparable to Cephalexin: Minimum Inhibitory Concentrations among Methicillin-Susceptible Staphylococcus aureus Isolates from Pediatric Musculoskeletal Infections.
Haynes AS, Prinzi A, Silveira LJ, Parker SK, Lampe JN, Kavanaugh JS, Horswill AR, Fish D. Haynes AS, et al. Microbiol Spectr. 2022 Aug 31;10(4):e0103922. doi: 10.1128/spectrum.01039-22. Epub 2022 Jun 22. Microbiol Spectr. 2022. PMID: 35730963 Free PMC article.
Both cefadroxil and cephalexin had MIC(50) values of 2 mug/mL and MIC(90) values of 4 mug/mL. ...While cephalexin is used more commonly, cefadroxil is excreted from the body more slowly; this generally allows patients to take cefadroxil less frequently than c …
Both cefadroxil and cephalexin had MIC(50) values of 2 mug/mL and MIC(90) values of 4 mug/mL. ...While cephalexin is used more common …
Cefadroxil-Induced Clostridium difficile Infection Following Total Knee Arthroplasty.
Angerett N, Ferguson C, Kahan M, Fitz D, Hallock R. Angerett N, et al. Arthroplast Today. 2022 Oct 12;18:52-56. doi: 10.1016/j.artd.2022.08.016. eCollection 2022 Dec. Arthroplast Today. 2022. PMID: 36267392 Free PMC article.
We describe a case report of a patient who underwent a primary TKA and subsequently developed Clostridium difficile colitis after an extended course of postoperative prophylactic oral cefadroxil. Following the C. difficile infection, the patient eventually developed bacter …
We describe a case report of a patient who underwent a primary TKA and subsequently developed Clostridium difficile colitis after an extende …
Cefadroxil Use for Musculoskeletal Infections in an Academic Pediatric Hospital.
Weslander E, Thomas H, Jeune R, Green M, Williams JV. Weslander E, et al. J Pediatric Infect Dis Soc. 2022 Dec 28;11(12):590-593. doi: 10.1093/jpids/piac104. J Pediatric Infect Dis Soc. 2022. PMID: 36112393
Forty-nine of 52 (94.2%) children with musculoskeletal infection (MSKI) were successfully treated with cefadroxil dosed at 30 mg/kg/day over a 10-year time period. Two failures were associated with poor medication adherence. Our study suggests that treatment of MSKI with …
Forty-nine of 52 (94.2%) children with musculoskeletal infection (MSKI) were successfully treated with cefadroxil dosed at 30 mg/kg/d …
Cefadroxil photodegradation processes sensitized by natural pigments: mechanistic aspects and impact on the antimicrobial function.
Urquiza AS, Reynoso A, Biondi MA, Spesia MB, Biasutti MA, Montejano HA, Reynoso E. Urquiza AS, et al. Photochem Photobiol Sci. 2024 Oct;23(10):1829-1840. doi: 10.1007/s43630-024-00633-3. Epub 2024 Sep 27. Photochem Photobiol Sci. 2024. PMID: 39331320
Cefadroxil is a widely used antibiotic with a low elimination efficiency in wastewater treatments plants, so it represents a contaminants of emerging concern that should be removed. The photosensitization process that involves natural pigments and visible sunlight can be o …
Cefadroxil is a widely used antibiotic with a low elimination efficiency in wastewater treatments plants, so it represents a contamin …
A Critical Review of Cephalexin and Cefadroxil for the Treatment of Acute Uncomplicated Lower Urinary Tract Infection in the Era of "Bad Bugs, Few Drugs".
Nguyen HM, Graber CJ. Nguyen HM, et al. Int J Antimicrob Agents. 2020 Oct;56(4):106085. doi: 10.1016/j.ijantimicag.2020.106085. Epub 2020 Jul 10. Int J Antimicrob Agents. 2020. PMID: 32659466 Review.
First-generation oral cephalosporins (cephalexin and cefadroxil) have traditionally been considered second-line treatment options for uncomplicated lower urinary tract infections (uLUTIs). ...Cephalexin can be conveniently administered as 500 mg twice or thrice daily, simi …
First-generation oral cephalosporins (cephalexin and cefadroxil) have traditionally been considered second-line treatment options for …
Why isn't cefadroxil used more often?
Corson AH, Myers BE, Dinges WL. Corson AH, et al. Am J Health Syst Pharm. 2016 Jun 1;73(11):754-5. doi: 10.2146/ajhp150841. Am J Health Syst Pharm. 2016. PMID: 27208060 No abstract available.
890 results