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65 results

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Page 1
Cefcapene pivoxil-induced hypocarnitinemic hypoglycemia in elderly man with subclinical ACTH deficiency: a case report.
Takahashi Y, Murayama M, Noda K, Yamakawa K, Koide Y, Yamada R, Hayashi M, Yasuda K. Takahashi Y, et al. BMC Endocr Disord. 2023 Mar 6;23(1):52. doi: 10.1186/s12902-023-01314-5. BMC Endocr Disord. 2023. PMID: 36872372 Free PMC article.
Hypoglycemia due to drug-induced hypocarnitinemia is quite rare, and there were few reports of pivoxil-containing cephalosporin (PCC)-induced hypocarnitinemia in adults. CASE PRESENTATION: We present a case of an 87-year-old man with malnutrition, and frailty. He developed …
Hypoglycemia due to drug-induced hypocarnitinemia is quite rare, and there were few reports of pivoxil-containing cephalosporin (PCC) …
Assessment of the Safety of Exposure to Cefcapene Pivoxil during the First Trimester of Pregnancy: A Prospective Cohort Study in Japan.
Miki Y, Koga Y, Taogoshi T, Itamura R, Yokooji T, Hishinuma K, Yakuwa N, Goto M, Murashima A, Matsuo H. Miki Y, et al. Biol Pharm Bull. 2024;47(7):1301-1306. doi: 10.1248/bpb.b24-00080. Biol Pharm Bull. 2024. PMID: 39010216 Free article.
Cefcapene pivoxil hydrochloride is an antibiotic often used by women who are or may be pregnant. ...The incidence of major malformations was 2.6% in the cefcapene pivoxil hydrochloride group and 1.8% in the control group. There were no significant diff …
Cefcapene pivoxil hydrochloride is an antibiotic often used by women who are or may be pregnant. ...The incidence of major mal …
Poor penetration of cefcapene into aqueous humor after oral administration of cefcapene pivoxil to patients undergoing cataract surgery.
Okamoto K, Asano S, Yamamoto T, Toyono T, Yamaguchi R, Okada Y, Okugawa S, Suzuki H, Moriya K, Aihara M. Okamoto K, et al. J Infect Chemother. 2020 Feb;26(2):312-315. doi: 10.1016/j.jiac.2019.08.004. Epub 2019 Aug 31. J Infect Chemother. 2020. PMID: 31481306
Aqueous humor penetration of cefcapene after 1-2 h, 2-3 h, and later than 3 h was 4.1, 7.9, and 13.5% respectively. CONCLUSIONS: Aqueous humor penetration of orally-administered cefcapene pivoxil in patients undergoing cataract surgery was poor. Therefore, …
Aqueous humor penetration of cefcapene after 1-2 h, 2-3 h, and later than 3 h was 4.1, 7.9, and 13.5% respectively. CONCLUSIONS: Aque …
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice.
Funayama E, Hosonuma M, Tajima K, Isobe J, Baba Y, Murayama M, Narikawa Y, Toyoda H, Tsurui T, Maruyama Y, Sasaki A, Amari Y, Yamazaki Y, Nakashima R, Uchiyama J, Nakano R, Shida M, Sasaki A, Udaka Y, Oguchi T, Sambe T, Kobayashi S, Tsuji M, Kiuchi Y, Kim YG, Wada S, Tsunoda T, Akiyama M, Nobe K, Kuramasu A, Yoshimura K. Funayama E, et al. Biomed Pharmacother. 2025 Jan;182:117749. doi: 10.1016/j.biopha.2024.117749. Epub 2024 Dec 23. Biomed Pharmacother. 2025. PMID: 39719740 Free article.
This study evaluated the effects of Bifidobacterium longum and Bifidobacterium infantis (BLBI) in a CT-26 subcutaneous tumor mouse model treated with anti-programmed cell death protein 1 antibody (alphaPD-1) and cefcapene pivoxil (CFPN-PI). BALB/c mice received dail …
This study evaluated the effects of Bifidobacterium longum and Bifidobacterium infantis (BLBI) in a CT-26 subcutaneous tumor mouse model tre …
Stability-Indicating HPLC Method for the Determination of Cefcapene Pivoxil.
Zalewski P, Cielecka-Piontek J, Garbacki P, Jelińska A, Karaźniewicz-Łada M. Zalewski P, et al. Chromatographia. 2013 Apr;76(7-8):387-391. doi: 10.1007/s10337-012-2318-1. Epub 2012 Sep 18. Chromatographia. 2013. PMID: 23555152 Free PMC article.
The stability-indicating LC assay method was developed and validated for quantitative determination of cefcapene pivoxil in the presence of degradation products formed during forced degradation studies. ...The method was applied successfully for the determination of …
The stability-indicating LC assay method was developed and validated for quantitative determination of cefcapene pivoxil in th …
Pharmacokinetics of cefcapene pivoxil and AS-924 in gastrectomized patients.
Fujimoto M. Fujimoto M. Int J Antimicrob Agents. 2001 Nov;18(5):489-94. doi: 10.1016/s0924-8579(01)00446-0. Int J Antimicrob Agents. 2001. PMID: 11711266
To investigate the effects of gastrectomy on the absorption of drugs, the blood concentrations of the active moieties, cefcapene (CCAP) and ceftizoxime (CTIZ), were determined in 36 gastrectomized patients after oral administration of cefcapene pivoxil (CCAP- …
To investigate the effects of gastrectomy on the absorption of drugs, the blood concentrations of the active moieties, cefcapene (CCA …
Relapsing Hypoglycemia Associated with Hypocarnitinemia Following Treatment with Cefcapene Pivoxil in an Elderly Man.
Hanai S, Iwata M, Terasawa T. Hanai S, et al. Intern Med. 2019 Oct 1;58(19):2891-2894. doi: 10.2169/internalmedicine.2339-18. Epub 2019 Jun 27. Intern Med. 2019. PMID: 31243204 Free PMC article.
Pivoxil-containing cephalosporins can result in symptomatic hypocarnitinemia in children. We herein report a case of an 85-year-old man at risk of carnitine deficiency who developed relapsing symptomatic hypoglycemia after treatment with cefcapene pivoxil for …
Pivoxil-containing cephalosporins can result in symptomatic hypocarnitinemia in children. We herein report a case of an 85-year-old m …
Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.
Murakami M, Masuda K, Utsunomiya R, Oda F, Namba C, Sayama K. Murakami M, et al. Dermatology. 2015;231(4):304-11. doi: 10.1159/000439401. Epub 2015 Oct 7. Dermatology. 2015. PMID: 26440444
We report 3 cases of PPP with PAO that did not improve upon administration of macrolide antibiotics with NSAIDs. After administration of cefcapene pivoxil hydrochloride (CFPN-PI), a third-generation cephalosporin, the swelling and sternoclavicular joint pain were pr …
We report 3 cases of PPP with PAO that did not improve upon administration of macrolide antibiotics with NSAIDs. After administration of …
Comparative clinical study of cefcapene pivoxil and cefteram pivoxil in chronic respiratory tract infections by a double-blind method.
Saito A, Hiraga Y, Watanabe A, Saito A, Shimada K, Kobayashi H, Odagiri S, Miki F, Soejima R, Oizumi K, Hara K, Nakashima M; Japanese Cefcapene Study Group. Saito A, et al. J Int Med Res. 2004 Nov-Dec;32(6):590-607. doi: 10.1177/147323000403200604. J Int Med Res. 2004. PMID: 15587753 Free article. Clinical Trial.
In a double-blind study, the efficacy and safety of the novel cephem antibiotic cefcapene pivoxil (CFPN-PI; 450 mg/day) was compared with cefteram pivoxil (CFTM-PI; 600 mg/day) in 171 patients with chronic respiratory tract infections. ...
In a double-blind study, the efficacy and safety of the novel cephem antibiotic cefcapene pivoxil (CFPN-PI; 450 mg/day) was co …
65 results