Celen S - Search Results

1

Translation of HDAC6 PET Imaging Using [¹⁸F]EKZ-001-cGMP Production and Measurement of HDAC6 Target Occupancy in Nonhuman Primates.

Celen S, Rokka J, Gilbert TM, Koole M, Vermeulen I, Serdons K, Schroeder FA, Wagner FF, Bleeser T, Hightower BG, Hu J, Rahal D, Beyzavi H, Vanduffel W, Van Laere K, Kranz JE, Hooker JM, Bormans G, Cawthorne CJ. Celen S, et al. ACS Chem Neurosci. 2020 Apr 1;11(7):1093-1101. doi: 10.1021/acschemneuro.0c00074. Epub 2020 Mar 19. ACS Chem Neurosci. 2020. PMID: 32159328 Free PMC article.

2

The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.

Balzarini J, Celen S, Karlsson A, de Groot T, Verbruggen A, Bormans G. Balzarini J, et al. Among authors: celen s. Antivir Chem Chemother. 2006;17(1):17-23. doi: 10.1177/095632020601700103. Antivir Chem Chemother. 2006. PMID: 16542002 Free article.

3

Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.

Chitneni SK, Deroose CM, Balzarini J, Gijsbers R, Celen SJ, de Groot TJ, Debyser Z, Mortelmans L, Verbruggen AM, Bormans GM. Chitneni SK, et al. J Med Chem. 2007 Mar 8;50(5):1041-9. doi: 10.1021/jm060964m. Epub 2007 Feb 14. J Med Chem. 2007. PMID: 17298046

4

Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction.

Chitneni SK, Serdons K, Evens N, Fonge H, Celen S, Deroose CM, Debyser Z, Mortelmans L, Verbruggen AM, Bormans GM. Chitneni SK, et al. Among authors: celen s. J Chromatogr A. 2008 May 2;1189(1-2):323-31. doi: 10.1016/j.chroma.2007.10.084. Epub 2007 Nov 1. J Chromatogr A. 2008. PMID: 18045609

5

A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.

Chitneni SK, Deroose CM, Balzarini J, Gijsbers R, Celen S, Debyser Z, Mortelmans L, Verbruggen AM, Bormans GM. Chitneni SK, et al. Among authors: celen s. J Med Chem. 2007 Dec 27;50(26):6627-37. doi: 10.1021/jm700971p. Epub 2007 Nov 30. J Med Chem. 2007. PMID: 18047266

6

Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography.

Celen S, Deroose C, de Groot T, Chitneni SK, Gijsbers R, Debyser Z, Mortelmans L, Verbruggen A, Bormans G. Celen S, et al. Bioconjug Chem. 2008 Feb;19(2):441-9. doi: 10.1021/bc700216d. Epub 2008 Jan 8. Bioconjug Chem. 2008. PMID: 18179161

7

Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.

Celen S, Cleynhens J, Deroose C, de Groot T, Ibrahimi A, Gijsbers R, Debyser Z, Mortelmans L, Verbruggen A, Bormans G. Celen S, et al. Bioorg Med Chem. 2009 Jul 15;17(14):5117-25. doi: 10.1016/j.bmc.2009.05.056. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19515568

8

Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.

Celen S, Koole M, De Angelis M, Sannen I, Chitneni SK, Alcazar J, Dedeurwaerdere S, Moechars D, Schmidt M, Verbruggen A, Langlois X, Van Laere K, Andrés JI, Bormans G. Celen S, et al. J Nucl Med. 2010 Oct;51(10):1584-91. doi: 10.2967/jnumed.110.077040. Epub 2010 Sep 16. J Nucl Med. 2010. PMID: 20847170 Free article.

9

Synthesis, in vivo occupancy, and radiolabeling of potent phosphodiesterase subtype-10 inhibitors as candidates for positron emission tomography imaging.

Andrés JI, De Angelis M, Alcázar J, Iturrino L, Langlois X, Dedeurwaerdere S, Lenaerts I, Vanhoof G, Celen S, Bormans G. Andrés JI, et al. Among authors: celen s. J Med Chem. 2011 Aug 25;54(16):5820-35. doi: 10.1021/jm200536d. Epub 2011 Aug 2. J Med Chem. 2011. PMID: 21777010

10

Recent advances in positron emission tomography (PET) radiotracers for imaging phosphodiesterases.

Andrés JI, De Angelis M, Alcázar J, Celen S, Bormans G. Andrés JI, et al. Among authors: celen s. Curr Top Med Chem. 2012;12(11):1224-36. doi: 10.2174/156802612800672853. Curr Top Med Chem. 2012. PMID: 22571785 Review.

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