Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

16 results
Filters applied: . Clear all
Page 1
Quantitative Proteomics of the Cancer Cell Line Encyclopedia.
Nusinow DP, et al. Cell 2020. PMID 31978347
To date, large-scale profiling of cell line collections including the Cancer Cell Line Encyclopedia (CCLE) has focused primarily on genetic information whereas deep interrogation of the proteome has remained out of reach. ...An analysis of microsatellite instable (MSI) cell lines reveals the dysregulation of specific protein complexes associated with surveillance of mutation and translation. ...
To date, large-scale profiling of cell line collections including the Cancer Cell Line Encyclopedia (CCLE) has focused primari …
FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle
Cader MZ, et al. Cell 2020. PMID 31978345 Free PMC article.
We report that FAMIN phosphorolytically cleaves adenosine into adenine and ribose-1-phosphate. Such activity was considered absent from eukaryotic metabolism. ...
We report that FAMIN phosphorolytically cleaves adenosine into adenine and ribose-1-phosphate. Such activity was considered absent fr …
Snake Venom Gland Organoids
Post Y, et al. Cell 2020. PMID 31978343
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types. Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids that recapitulate essential features of the pertinent epithelium. ...Single-cell RNA sequencing of both organoids and primary tissue identifies distinct venom-expressing cell types as well as proliferative cells expressing homologs of known mammalian stem cell markers. ...
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types. Under defined growth factor conditions, such …
Science that Inspires
Cell Press Team . Cell 2020. PMID 31978336
All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1.
Fan LZ, et al. Cell 2020. PMID 31978320
Cortical layer 1 (L1) interneurons have been proposed as a hub for attentional modulation of underlying cortex, but the transformations that this circuit implements are not known. ...
Cortical layer 1 (L1) interneurons have been proposed as a hub for attentional modulation of underlying cortex, but the transformatio …
Widespread Transcriptional Scanning in the Testis Modulates Gene Evolution Rates
Xia B, et al. Cell 2020. PMID 31978344
Our single-cell transcriptomic data of human and mouse spermatogenesis provide evidence that this widespread transcription maintains DNA sequence integrity in the male germline by correcting DNA damage through a mechanism we term transcriptional scanning. ...
Our single-cell transcriptomic data of human and mouse spermatogenesis provide evidence that this widespread transcription maintains …
16 results
Jump to page
Feedback