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Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.
Tan T, Wu J, Si C, Dai S, Zhang Y, Sun N, Zhang E, Shao H, Si W, Yang P, Wang H, Chen Z, Zhu R, Kang Y, Hernandez-Benitez R, Martinez Martinez L, Nuñez Delicado E, Berggren WT, Schwarz M, Ai Z, Li T, Rodriguez Esteban C, Ji W, Niu Y, Izpisua Belmonte JC. Tan T, et al. Cell. 2021 Apr 15;184(8):2020-2032.e14. doi: 10.1016/j.cell.2021.03.020. Cell. 2021. PMID: 33861963
We demonstrate that hEPSCs survived, proliferated, and generated several peri- and early post-implantation cell lineages inside monkey embryos. We also uncovered signaling events underlying interspecific crosstalk that may help shape the unique developmental trajectories o …
We demonstrate that hEPSCs survived, proliferated, and generated several peri- and early post-implantation cell lineages inside monke …
Neu(ronal) custodians of cutaneous immunity.
Mansfield KP, Naik S. Mansfield KP, et al. Cell. 2021 Apr 15;184(8):1968-1970. doi: 10.1016/j.cell.2021.03.040. Cell. 2021. PMID: 33861962
Sensory neurons have surfaced as key instigators of skin inflammation. In this issue of Cell, Zhang et al. define an anti-inflammatory Langerhans cell (LC)-neuron-mast cell (MC) circuit that underlies skin immune homeostasis. ...
Sensory neurons have surfaced as key instigators of skin inflammation. In this issue of Cell, Zhang et al. define an anti-inflammator …
Founder cells shape brain evolution.
Liu J, Silver DL. Liu J, et al. Cell. 2021 Apr 15;184(8):1965-1967. doi: 10.1016/j.cell.2021.03.045. Cell. 2021. PMID: 33861961
Toward a fine-scale population health monitoring system.
Belbin GM, Cullina S, Wenric S, Soper ER, Glicksberg BS, Torre D, Moscati A, Wojcik GL, Shemirani R, Beckmann ND, Cohain A, Sorokin EP, Park DS, Ambite JL, Ellis S, Auton A; CBIPM Genomics Team; Regeneron Genetics Center, Bottinger EP, Cho JH, Loos RJF, Abul-Husn NS, Zaitlen NA, Gignoux CR, Kenny EE. Belbin GM, et al. Cell. 2021 Apr 15;184(8):2068-2083.e11. doi: 10.1016/j.cell.2021.03.034. Cell. 2021. PMID: 33861964
Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States.
Washington NL, Gangavarapu K, Zeller M, Bolze A, Cirulli ET, Schiabor Barrett KM, Larsen BB, Anderson C, White S, Cassens T, Jacobs S, Levan G, Nguyen J, Ramirez JM 3rd, Rivera-Garcia C, Sandoval E, Wang X, Wong D, Spencer E, Robles-Sikisaka R, Kurzban E, Hughes LD, Deng X, Wang C, Servellita V, Valentine H, De Hoff P, Seaver P, Sathe S, Gietzen K, Sickler B, Antico J, Hoon K, Liu J, Harding A, Bakhtar O, Basler T, Austin B, MacCannell D, Isaksson M, Febbo PG, Becker D, Laurent M, McDonald E, Yeo GW, Knight R, Laurent LC, de Feo E, Worobey M, Chiu CY, Suchard MA, Lu JT, Lee W, Andersen KG. Washington NL, et al. Cell. 2021 Mar 30:S0092-8674(21)00383-4. doi: 10.1016/j.cell.2021.03.052. Online ahead of print. Cell. 2021. PMID: 33861950 Free PMC article.
Is genetic ancestry a tool to combat health disparities?
Chisholm RL. Chisholm RL. Cell. 2021 Apr 15;184(8):1964-1965. doi: 10.1016/j.cell.2021.03.038. Cell. 2021. PMID: 33861960
Currently the social construct of race and ethnicity is far from precise, serving as a poor proxy for ancestry. In this issue of Cell, Belbin et al. provide an interesting framework for better characterizing population substructure in a diverse urban environment....
Currently the social construct of race and ethnicity is far from precise, serving as a poor proxy for ancestry. In this issue of Cell
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