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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity.
Andrews LP, Butler SC, Cui J, Cillo AR, Cardello C, Liu C, Brunazzi EA, Baessler A, Xie B, Kunning SR, Ngiow SF, Huang YJ, Manne S, Sharpe AH, Delgoffe GM, Wherry EJ, Kirkwood JM, Bruno TC, Workman CJ, Vignali DAA. Andrews LP, et al. Cell. 2024 Aug 8;187(16):4355-4372.e22. doi: 10.1016/j.cell.2024.07.016. Cell. 2024. PMID: 39121848
Guidelines for minimal information on cellular senescence experimentation in vivo.
Ogrodnik M, Carlos Acosta J, Adams PD, d'Adda di Fagagna F, Baker DJ, Bishop CL, Chandra T, Collado M, Gil J, Gorgoulis V, Gruber F, Hara E, Jansen-Dürr P, Jurk D, Khosla S, Kirkland JL, Krizhanovsky V, Minamino T, Niedernhofer LJ, Passos JF, Ring NAR, Redl H, Robbins PD, Rodier F, Scharffetter-Kochanek K, Sedivy JM, Sikora E, Witwer K, von Zglinicki T, Yun MH, Grillari J, Demaria M. Ogrodnik M, et al. Cell. 2024 Aug 8;187(16):4150-4175. doi: 10.1016/j.cell.2024.05.059. Cell. 2024. PMID: 39121846 Free article. Review.
The need to diversify genomic studies: Insights from Andean highlanders and Amazonians.
Alvim I, Silva-Carvalho C, Mendes de Aquino M, Borda V, Sanchez C, Padilla C, Cáceres O, Rezende-Diniz I, Saraiva-Duarte J, Faria-Costa L, Santolalla ML, Rodrigues-Soares F, Zolini C, Llerena A, O'Connor TD, Gilman RH, Guio H, Tarazona-Santos E. Alvim I, et al. Cell. 2024 Sep 5;187(18):4819-4823. doi: 10.1016/j.cell.2024.07.009. Epub 2024 Aug 8. Cell. 2024. PMID: 39121858