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GUK1 activation is a metabolic liability in lung cancer.
Schneider JL, Kurmi K, Dai Y, Dhiman I, Joshi S, Gassaway BM, Johnson CW, Jones N, Li Z, Joschko CP, Fujino T, Paulo JA, Yoda S, Baquer G, Ruiz D, Stopka SA, Kelley L, Do A, Mino-Kenudson M, Sequist LV, Lin JJ, Agar NYR, Gygi SP, Haigis KM, Hata AN, Haigis MC. Schneider JL, et al. Cell. 2025 Mar 6;188(5):1248-1264.e23. doi: 10.1016/j.cell.2025.01.024. Epub 2025 Feb 6. Cell. 2025. PMID: 39919745
Tumor "age" in early-onset colorectal cancer.
Mauri G, Patelli G, Crisafulli G, Siena S, Bardelli A. Mauri G, et al. Cell. 2025 Feb 6;188(3):589-593. doi: 10.1016/j.cell.2024.12.003. Cell. 2025. PMID: 39919707 Review.