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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1948 1
1950 3
1951 2
1952 3
1953 10
1954 6
1955 5
1956 9
1957 12
1958 14
1959 50
1960 14
1961 18
1962 22
1963 33
1964 49
1965 68
1966 60
1967 72
1968 98
1969 124
1970 125
1971 156
1972 188
1973 205
1974 191
1975 134
1976 150
1977 111
1978 131
1979 153
1980 139
1981 134
1982 151
1983 120
1984 171
1985 167
1986 178
1987 159
1988 186
1989 176
1990 197
1991 198
1992 227
1993 219
1994 245
1995 321
1996 396
1997 415
1998 563
1999 572
2000 647
2001 599
2002 640
2003 583
2004 611
2005 650
2006 661
2007 771
2008 808
2009 756
2010 836
2011 854
2012 854
2013 906
2014 860
2015 853
2016 809
2017 838
2018 932
2019 944
2020 990
2021 1108
2022 1057
2023 997
2024 1020
2025 1110
2026 766
2027 1

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27,229 results

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Page 1
Ceramides in Skin Health and Disease: An Update.
Uchida Y, Park K. Uchida Y, et al. Am J Clin Dermatol. 2021 Nov;22(6):853-866. doi: 10.1007/s40257-021-00619-2. Epub 2021 Jul 20. Am J Clin Dermatol. 2021. PMID: 34283373 Review.
In addition, hereditary abnormalities of some ichthyoses are associated with an epidermal unique ceramide species, omega-O-acylceramide. Ceramides also serve as lipid modulators to regulate cellular functions, including cell cycle arrest, differentiation, and apopto …
In addition, hereditary abnormalities of some ichthyoses are associated with an epidermal unique ceramide species, omega-O-acylcerami …
Ceramides and Skin Health: New Insights.
Yong TL, Zaman R, Rehman N, Tan CK. Yong TL, et al. Exp Dermatol. 2025 Feb;34(2):e70042. doi: 10.1111/exd.70042. Exp Dermatol. 2025. PMID: 39912256 Review.
Approaches to increase ceramide levels include directly replenishing lost ceramides with natural extracts, synthetic pseudo-ceramides, or ceramide-like analogues, as well as using supplements that stimulate the body's natural ceramide production …
Approaches to increase ceramide levels include directly replenishing lost ceramides with natural extracts, synthetic pseudo- …
Ceramides and Acute Kidney Injury.
Nicholson RJ, Holland WL, Summers SA. Nicholson RJ, et al. Semin Nephrol. 2022 May;42(3):151281. doi: 10.1016/j.semnephrol.2022.10.007. Epub 2022 Nov 18. Semin Nephrol. 2022. PMID: 36404212 Free PMC article. Review.
Of the lipids that accumulate in injured renal tissues, ceramides are potent regulators of metabolism and cell fate. Up-regulation of ceramide synthesis is a common feature shared across several AKI etiologies in vitro and in vivo. ...Furthermore, we discuss the bod …
Of the lipids that accumulate in injured renal tissues, ceramides are potent regulators of metabolism and cell fate. Up-regulation of …
Ceramides as Novel Disease Biomarkers.
Kurz J, Parnham MJ, Geisslinger G, Schiffmann S. Kurz J, et al. Trends Mol Med. 2019 Jan;25(1):20-32. doi: 10.1016/j.molmed.2018.10.009. Epub 2018 Nov 23. Trends Mol Med. 2019. PMID: 30477968 Review.
Ceramides or ceramide panel combinations have been proposed as specific disease biomarkers that could be detected in diseased tissue, synovial fluid, cerebrospinal fluid (CSF), and blood. This article reviews ceramide modulation in a selection of different di
Ceramides or ceramide panel combinations have been proposed as specific disease biomarkers that could be detected in diseased
Many ceramides.
Hannun YA, Obeid LM. Hannun YA, et al. J Biol Chem. 2011 Aug 12;286(32):27855-62. doi: 10.1074/jbc.R111.254359. Epub 2011 Jun 21. J Biol Chem. 2011. PMID: 21693702 Free PMC article. Review.
Intensive research over the past 2 decades has implicated ceramide in the regulation of several cell responses. However, emerging evidence points to dramatic complexities in ceramide metabolism and structure that defy the prevailing unifying hypothesis on ceramid
Intensive research over the past 2 decades has implicated ceramide in the regulation of several cell responses. However, emerging evi …
Visualizing bioactive ceramides.
Canals D, Salamone S, Hannun YA. Canals D, et al. Chem Phys Lipids. 2018 Nov;216:142-151. doi: 10.1016/j.chemphyslip.2018.09.013. Epub 2018 Sep 25. Chem Phys Lipids. 2018. PMID: 30266560 Free PMC article. Review.
Recently, the 'Many Ceramides' hypothesis focuses on distinct pools of subcellular ceramides and ceramide species as potential defined bioactive entities. ...However, a few ceramide binding proteins have been reported, and a smaller subgroup within the …
Recently, the 'Many Ceramides' hypothesis focuses on distinct pools of subcellular ceramides and ceramide species as po …
Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification.
Hilvo M, Vasile VC, Donato LJ, Hurme R, Laaksonen R. Hilvo M, et al. Front Endocrinol (Lausanne). 2020 Sep 29;11:570628. doi: 10.3389/fendo.2020.570628. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33133018 Free PMC article. Review.
Ceramides are bioactive lipids that have an important role in many cellular functions such as apoptosis and inflammation. ...A direct cause-effect relationship between CVD and ceramide has not been established to date. As ceramide-specific medications are bei
Ceramides are bioactive lipids that have an important role in many cellular functions such as apoptosis and inflammation. ...A direct
Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy.
Alizadeh J, da Silva Rosa SC, Weng X, Jacobs J, Lorzadeh S, Ravandi A, Vitorino R, Pecic S, Zivkovic A, Stark H, Shojaei S, Ghavami S. Alizadeh J, et al. Eur J Cell Biol. 2023 Sep;102(3):151337. doi: 10.1016/j.ejcb.2023.151337. Epub 2023 Jun 26. Eur J Cell Biol. 2023. PMID: 37392580 Free article. Review.
Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptosis and autophagy in the context of cancer. ...Therefore, in the current review paper we discuss the impact of ceramide synthases and …
Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptos …
Function of ceramides in the skin and its relationship with skin disease.
Huang W, Liu J, Zhao L, He H. Huang W, et al. J Steroid Biochem Mol Biol. 2025 Nov;254:106842. doi: 10.1016/j.jsbmb.2025.106842. Epub 2025 Aug 11. J Steroid Biochem Mol Biol. 2025. PMID: 40803540 Review.
In the cosmetic industry, ceramides are used for skin barrier repair and moisturization. However, their poor water solubility necessitates the development of effective delivery systems. Alternatively, exogenous substances can be utilized to promote ceramide synthesi …
In the cosmetic industry, ceramides are used for skin barrier repair and moisturization. However, their poor water solubility necessi …
Ceramides and depression: A systematic review.
Dinoff A, Herrmann N, Lanctôt KL. Dinoff A, et al. J Affect Disord. 2017 Apr 15;213:35-43. doi: 10.1016/j.jad.2017.02.008. Epub 2017 Feb 7. J Affect Disord. 2017. PMID: 28189963
Evidence for altered ceramide metabolism in depression is present, but data for a causal role of ceramides in depression are lacking. ...Furthermore, a lack of specificity of which ceramides were altered in depression was common. CONCLUSIONS: Pharmacotherapy …
Evidence for altered ceramide metabolism in depression is present, but data for a causal role of ceramides in depression are l …
27,229 results
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