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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1971 3
1972 5
1973 4
1974 3
1975 4
1976 2
1977 2
1978 1
1981 1
1983 1
1985 1
1986 3
1987 2
1988 4
1989 6
1990 4
1991 4
1992 14
1993 13
1994 10
1995 15
1996 9
1997 15
1998 16
1999 19
2000 24
2001 17
2002 23
2003 25
2004 27
2005 26
2006 22
2007 34
2008 20
2009 30
2010 32
2011 21
2012 19
2013 22
2014 17
2015 24
2016 21
2017 24
2018 22
2019 24
2020 27
2021 30
2022 40
2023 24
2024 5

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707 results

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Page 1
Monitoring α-synuclein aggregation.
Estaun-Panzano J, Arotcarena ML, Bezard E. Estaun-Panzano J, et al. Neurobiol Dis. 2023 Jan;176:105966. doi: 10.1016/j.nbd.2022.105966. Epub 2022 Dec 15. Neurobiol Dis. 2023. PMID: 36527982 Free PMC article. Review.
Synucleinopathies, including Parkinson's disease (PD), dementia with Lewy Bodies (DLB), and multiple system atrophy (MSA), are characterized by the misfolding and subsequent aggregation of alpha-synuclein (alpha-syn) that accumulates in cytoplasmic inclusions bodies
Synucleinopathies, including Parkinson's disease (PD), dementia with Lewy Bodies (DLB), and multiple system atrophy (MSA), are charac …
Selective neuronal vulnerability in Parkinson disease.
Surmeier DJ, Obeso JA, Halliday GM. Surmeier DJ, et al. Nat Rev Neurosci. 2017 Jan 20;18(2):101-113. doi: 10.1038/nrn.2016.178. Nat Rev Neurosci. 2017. PMID: 28104909 Free PMC article. Review.
It is widely believed that LP appears early in the disease and spreads in synaptically coupled brain networks, driving neuronal dysfunction and death. However, post-mortem analysis of human brains and connectome-mapping studies show that the pattern of LP in cPD is not con …
It is widely believed that LP appears early in the disease and spreads in synaptically coupled brain networks, driving neuronal dysfu …
Stages in the development of Parkinson's disease-related pathology.
Braak H, Ghebremedhin E, Rüb U, Bratzke H, Del Tredici K. Braak H, et al. Cell Tissue Res. 2004 Oct;318(1):121-34. doi: 10.1007/s00441-004-0956-9. Epub 2004 Aug 24. Cell Tissue Res. 2004. PMID: 15338272 Review.
The synucleinopathy, idiopathic Parkinson's disease, is a multisystem disorder that involves only a few predisposed nerve cell types in specific regions of the human nervous system. The intracerebral formation of abnormal proteinaceous Lewy bodies and Lewy neurites begins …
The synucleinopathy, idiopathic Parkinson's disease, is a multisystem disorder that involves only a few predisposed nerve cell types in spec …
Alpha-synucleinopathies.
Alafuzoff I, Hartikainen P. Alafuzoff I, et al. Handb Clin Neurol. 2017;145:339-353. doi: 10.1016/B978-0-12-802395-2.00024-9. Handb Clin Neurol. 2017. PMID: 28987181 Review.
A neurodegenerative disorder displaying an altered alpha-synuclein (alphaS) in the brain tissue is called alpha-synucleinopathy (alphaS-pathy) and incorporates clinical entities such as Parkinson disease (PD), PD with dementia, dementia with Lewy bodies, and multipl …
A neurodegenerative disorder displaying an altered alpha-synuclein (alphaS) in the brain tissue is called alpha-synucleinopathy (alph …
α-Synuclein pathology in Parkinson's disease and related α-synucleinopathies.
Henderson MX, Trojanowski JQ, Lee VM. Henderson MX, et al. Neurosci Lett. 2019 Sep 14;709:134316. doi: 10.1016/j.neulet.2019.134316. Epub 2019 Jun 3. Neurosci Lett. 2019. PMID: 31170426 Free PMC article. Review.
Over 20 years ago, the synaptic protein alpha-synuclein was identified as the primary component of the Lewy bodies (LBs) that are a sine qua non of Parkinson's disease (PD). ...The stereotypical progression of alpha-synuclein pathology through the brain over time su …
Over 20 years ago, the synaptic protein alpha-synuclein was identified as the primary component of the Lewy bodies (LBs) that are a s …
Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen.
Braak H, Rüb U, Gai WP, Del Tredici K. Braak H, et al. J Neural Transm (Vienna). 2003 May;110(5):517-36. doi: 10.1007/s00702-002-0808-2. J Neural Transm (Vienna). 2003. PMID: 12721813 Review.
The progressive, neurodegenerative process underlying idiopathic Parkinson's disease is associated with the formation of proteinaceous inclusion bodies that involve a few susceptible neuronal types of the human nervous system. In the lower brain stem, the pro …
The progressive, neurodegenerative process underlying idiopathic Parkinson's disease is associated with the formation of proteinaceous in
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium.
McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, Costa D, Del Ser T, Dubois B, Galasko D, Gauthier S, Goetz CG, Gomez-Tortosa E, Halliday G, Hansen LA, Hardy J, Iwatsubo T, Kalaria RN, Kaufer D, Kenny RA, Korczyn A, Kosaka K, Lee VM, Lees A, Litvan I, Londos E, Lopez OL, Minoshima S, Mizuno Y, Molina JA, Mukaetova-Ladinska EB, Pasquier F, Perry RH, Schulz JB, Trojanowski JQ, Yamada M; Consortium on DLB. McKeith IG, et al. Neurology. 2005 Dec 27;65(12):1863-72. doi: 10.1212/01.wnl.0000187889.17253.b1. Epub 2005 Oct 19. Neurology. 2005. PMID: 16237129 Review.
The dementia with Lewy bodies (DLB) Consortium has revised criteria for the clinical and pathologic diagnosis of DLB incorporating new information about the core clinical features and suggesting improved methods to assess them. ...
The dementia with Lewy bodies (DLB) Consortium has revised criteria for the clinical and pathologic diagnosis of DLB incorporating ne …
The heterogeneity of Parkinson's disease.
Wüllner U, Borghammer P, Choe CU, Csoti I, Falkenburger B, Gasser T, Lingor P, Riederer P. Wüllner U, et al. J Neural Transm (Vienna). 2023 Jun;130(6):827-838. doi: 10.1007/s00702-023-02635-4. Epub 2023 May 11. J Neural Transm (Vienna). 2023. PMID: 37169935 Free PMC article. Review.
We outline several pathophysiological concepts, pathways and mechanisms, including the presumed roles of alpha-synuclein misfolding and aggregation, Lewy bodies, oxidative stress, iron and melanin, deficient autophagy processes, insulin and incretin signaling, T-cell autoi …
We outline several pathophysiological concepts, pathways and mechanisms, including the presumed roles of alpha-synuclein misfolding and aggr …
Trinucleotide repeat disorders.
Den Dunnen WFA. Den Dunnen WFA. Handb Clin Neurol. 2017;145:383-391. doi: 10.1016/B978-0-12-802395-2.00027-4. Handb Clin Neurol. 2017. PMID: 28987184 Review.
In fragile X-associated tremor and ataxia, SCA6 and SCA12 ubiquitin/p62-positive and 1C2-negative inclusion bodies can be observed. In the other diseases proteinaceous inclusions are not found. ...
In fragile X-associated tremor and ataxia, SCA6 and SCA12 ubiquitin/p62-positive and 1C2-negative inclusion bodies can be obse …
The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates.
Wakabayashi K, Tanji K, Mori F, Takahashi H. Wakabayashi K, et al. Neuropathology. 2007 Oct;27(5):494-506. doi: 10.1111/j.1440-1789.2007.00803.x. Neuropathology. 2007. PMID: 18018486 Review.
The histological hallmark of Parkinson's disease (PD) is the presence of fibrillar aggregates called Lewy bodies (LBs). LB formation has been considered to be a marker for neuronal degeneration, because neuronal loss is found in the predilection sites for LBs. ...Alpha-syn …
The histological hallmark of Parkinson's disease (PD) is the presence of fibrillar aggregates called Lewy bodies (LBs). LB formation …
707 results