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The preventive anti-oxidant action of thiazolidinediones: a new therapeutic prospect in diabetes and insulin resistance.
Da Ros R, Assaloni R, Ceriello A. Da Ros R, et al. Diabet Med. 2004 Nov;21(11):1249-52. doi: 10.1111/j.1464-5491.2004.01312.x. Diabet Med. 2004. PMID: 15498094 Review.
RESULTS: Thiazolidinediones are a new class of insulin-sensitizing agents. They inhibit intracellular free radical overproduction. ...CONCLUSIONS: The availability of compounds that simultaneously decrease hyperglycaemia, restore insulin resistance and inhibit pathways act …
RESULTS: Thiazolidinediones are a new class of insulin-sensitizing agents. They inhibit intracellular free radical overproduction. .. …
Sod and GSH inhibit the high glucose-induced oxidative damage and the PDGF increased secretion in cultured human endothelial cells.
Curcio F, Pegoraro I, Dello Russo P, Falleti E, Perrella G, Ceriello A. Curcio F, et al. Thromb Haemost. 1995 Sep;74(3):969-73. Thromb Haemost. 1995. PMID: 8571331
Poor control of blood glucose has been established as a key pathogenetic mechanism in the vascular complications of diabetes. ...These results suggest that antioxidants may be a helpful therapeutic adjuvant to reduce the vascular complications of diabetes....
Poor control of blood glucose has been established as a key pathogenetic mechanism in the vascular complications of diabetes. ...Thes …
Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly(ADP-ribose) polymerase.
Piconi L, Quagliaro L, Da Ros R, Assaloni R, Giugliano D, Esposito K, Szabó C, Ceriello A. Piconi L, et al. J Thromb Haemost. 2004 Aug;2(8):1453-9. doi: 10.1111/j.1538-7836.2004.00835.x. J Thromb Haemost. 2004. PMID: 15304054
In this study we have investigated the effects of constantly high and intermittently high glucose on nitrotyrosine formation (a marker of nitrosative stress) and adhesion molecule (ICAM-1, VCAM-1 and E-selectin), as well as on interleukin (IL)-6 expression in human umbilic …
In this study we have investigated the effects of constantly high and intermittently high glucose on nitrotyrosine formation (a marke …
Postprandial hyperglycemia and cardiovascular complications of diabetes.
Ceriello A. Ceriello A. Journ Annu Diabetol Hotel Dieu. 2006:75-8. Journ Annu Diabetol Hotel Dieu. 2006. PMID: 17051851 Review. No abstract available.
Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus.
Bonora E, Corrao G, Bagnardi V, Ceriello A, Comaschi M, Montanari P, Meigs JB. Bonora E, et al. Diabetologia. 2006 May;49(5):846-54. doi: 10.1007/s00125-006-0203-x. Epub 2006 Mar 11. Diabetologia. 2006. PMID: 16532323 Clinical Trial.
RESULTS: A post-prandial blood glucose value >8.89 mmol/l (160 mg/dl) was recorded at least once in 84% of patients, and 81% of patients had at least one Delta glucose > or =2.22 mmol/l (40 mg/dl). ...CONCLUSIONS/INTERPRETATION: These results indicate that post-prand …
RESULTS: A post-prandial blood glucose value >8.89 mmol/l (160 mg/dl) was recorded at least once in 84% of patients, and 81% of pa …
What does postprandial hyperglycaemia mean?
Heine RJ, Balkau B, Ceriello A, Del Prato S, Horton ES, Taskinen MR. Heine RJ, et al. Diabet Med. 2004 Mar;21(3):208-13. doi: 10.1111/j.1464-5491.2004.01149.x. Diabet Med. 2004. PMID: 15008828 Review.
Using the ADA statement as a starting point and including the more recent American College of Endocrinology guidelines on glycaemic control, a panel of experts in diabetes met to review the role of PPG within the context of the overall metabolic syndrome, in the dev …
Using the ADA statement as a starting point and including the more recent American College of Endocrinology guidelines on glycaemic c …
The possible role of postprandial hyperglycaemia in the pathogenesis of diabetic complications.
Ceriello A. Ceriello A. Diabetologia. 2003 Mar;46 Suppl 1:M9-16. doi: 10.1007/s00125-002-0931-5. Epub 2002 Nov 7. Diabetologia. 2003. PMID: 12652353 Review.
The role of oxidative stress as a mediator of acute hyperglycaemia is further discussed. More investigation in this area is required so that treatment can be eventually individualised. ...
The role of oxidative stress as a mediator of acute hyperglycaemia is further discussed. More investigation in this area is required …
Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
Prattichizzo F, Giuliani A, De Nigris V, Pujadas G, Ceka A, La Sala L, Genovese S, Testa R, Procopio AD, Olivieri F, Ceriello A. Prattichizzo F, et al. Diabetes Obes Metab. 2016 Sep;18(9):855-67. doi: 10.1111/dom.12688. Epub 2016 Jun 22. Diabetes Obes Metab. 2016. PMID: 27161301 Free PMC article. Review.
They can be secreted by living cells and taken up in active form by recipient cells, providing a new communication tool between tissues and organs. MiRNA deregulation has been associated with the development and progression of a number of age-related diseases, inclu …
They can be secreted by living cells and taken up in active form by recipient cells, providing a new communication tool between tissu …
Clinical implications of oxidative stress and potential role of natural antioxidants in diabetic vascular complications.
Ceriello A, Testa R, Genovese S. Ceriello A, et al. Nutr Metab Cardiovasc Dis. 2016 Apr;26(4):285-92. doi: 10.1016/j.numecd.2016.01.006. Epub 2016 Jan 19. Nutr Metab Cardiovasc Dis. 2016. PMID: 27036849 Review.
DATA SYNTHESIS: Some prospective studies show a direct correlation between an increase in OxS biomarkers and the appearance of diabetes complications. ...A synergistic action in this respect could convincingly be obtained with a balanced 'Mediterranean Diet' …
DATA SYNTHESIS: Some prospective studies show a direct correlation between an increase in OxS biomarkers and the appearance of diabet …
Lispro insulin in people with non-alcoholic liver cirrhosis and type 2 diabetes mellitus.
Gentile S, Guarino G, Strollo F, Romano M, Genovese S, Masarone M, Ceriello A. Gentile S, et al. Diabetes Res Clin Pract. 2016 Mar;113:179-86. doi: 10.1016/j.diabres.2015.12.006. Epub 2016 Jan 9. Diabetes Res Clin Pract. 2016. PMID: 26803356 Clinical Trial.
METHODS: 108 people with T2DM and CLD were randomly allocated to RHI or lispro according to a 12+12 week cross-over protocol. A 1-week continuous glucose monitoring (CGM) session was performed at the end of each treatment period followed by a standard meal te …
METHODS: 108 people with T2DM and CLD were randomly allocated to RHI or lispro according to a 12+12 week cross-over protocol. A
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