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Development and validation of a high-throughput method for the quantitative analysis of D-amphetamine in rat blood using liquid chromatography/MS3 on a hybrid triple quadrupole-linear ion trap mass spectrometer and its application to a pharmacokinetic study.
Cesari N, Fontana S, Montanari D, Braggio S. Cesari N, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jan 1;878(1):21-8. doi: 10.1016/j.jchromb.2009.11.009. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 19945359
In vivo rat PK profiling in drug discovery: new challenges.
Zonzini L, Bianchi F, Cesari N, Sartori M. Zonzini L, et al. Among authors: cesari n. Expert Opin Drug Discov. 2010 Nov;5(11):1031-7. doi: 10.1517/17460441.2010.509396. Epub 2010 Jul 27. Expert Opin Drug Discov. 2010. PMID: 22827743 Review.
Discovery of a novel class of inhaled dual pharmacology muscarinic antagonist and β2 agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD).
Rancati F, Linney ID, Rizzi A, Delcanale M, Knight CK, Schmidt W, Pastore F, Riccardi B, Mileo V, Carnini C, Cesari N, Blackaby WP, Patacchini R, Carzaniga L. Rancati F, et al. Among authors: cesari n. Bioorg Med Chem Lett. 2021 Jun 1;41:127975. doi: 10.1016/j.bmcl.2021.127975. Epub 2021 Mar 19. Bioorg Med Chem Lett. 2021. PMID: 33753262
Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Carzaniga L, Linney ID, Rizzi A, Delcanale M, Schmidt W, Knight CK, Pastore F, Miglietta D, Carnini C, Cesari N, Riccardi B, Mileo V, Venturi L, Moretti E, Blackaby WP, Patacchini R, Accetta A, Biagetti M, Bassani F, Tondelli M, Murgo A, Battipaglia L, Villetti G, Puccini P, Catinella S, Civelli M, Rancati F. Carzaniga L, et al. Among authors: cesari n. J Med Chem. 2022 Aug 11;65(15):10233-10250. doi: 10.1021/acs.jmedchem.2c00609. Epub 2022 Jul 28. J Med Chem. 2022. PMID: 35901125
24 results