Chabes A - Search Results

1

The modifiers that cause changes in gene essentiality.

Batté A, Bosch-Guiteras N, Pons C, Ota M, Lopes M, Sharma S, Tellini N, Paltenghi C, Conti M, Kan KT, Ho UL, Wiederkehr M, Barraud J, Ashe M, Aloy P, Liti G, Chabes A, Parts L, van Leeuwen J. Batté A, et al. Among authors: chabes a. Cell Syst. 2026 Mar 2:101515. doi: 10.1016/j.cels.2025.101515. Online ahead of print. Cell Syst. 2026. PMID: 41775267 Free article.

2

dNTP concentrations do not increase in mammalian cells in response to DNA damage.

Das B, Mishra P, Pandey P, Sharma S, Chabes A. Das B, et al. Among authors: chabes a. Cell Metab. 2022 Dec 6;34(12):1895-1896. doi: 10.1016/j.cmet.2022.11.002. Cell Metab. 2022. PMID: 36476929 Free article.

3

Chl1 helicase controls replication fork progression by regulating dNTP pools.

Batté A, van der Horst SC, Tittel-Elmer M, Sun SM, Sharma S, van Leeuwen J, Chabes A, van Attikum H. Batté A, et al. Among authors: chabes a. Life Sci Alliance. 2022 Jan 11;5(4):e202101153. doi: 10.26508/lsa.202101153. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35017203 Free PMC article.

4

Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity.

Mertz TM, Sharma S, Chabes A, Shcherbakova PV. Mertz TM, et al. Among authors: chabes a. Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2467-76. doi: 10.1073/pnas.1422934112. Epub 2015 Mar 31. Proc Natl Acad Sci U S A. 2015. PMID: 25827231 Free PMC article.

5

Isocratic HPLC analysis for the simultaneous determination of dNTPs, rNTPs and ADP in biological samples.

Ranjbarian F, Sharma S, Falappa G, Taruschio W, Chabes A, Hofer A. Ranjbarian F, et al. Among authors: chabes a. Nucleic Acids Res. 2022 Feb 22;50(3):e18. doi: 10.1093/nar/gkab1117. Nucleic Acids Res. 2022. PMID: 34850106 Free PMC article.

6

Quantitative Analysis of Nucleoside Triphosphate Pools in Mouse Muscle Using Hydrophilic Interaction Liquid Chromatography Coupled with Tandem Mass Spectrometry Detection.

Sharma S, Kong Z, Jia S, Tran P, Nilsson AK, Chabes A. Sharma S, et al. Among authors: chabes a. Methods Mol Biol. 2023;2615:267-280. doi: 10.1007/978-1-0716-2922-2_19. Methods Mol Biol. 2023. PMID: 36807798

7

Impairment of the non-catalytic subunit Dpb2 of DNA Pol ɛ results in increased involvement of Pol δ on the leading strand.

Dmowski M, Makiela-Dzbenska K, Sharma S, Chabes A, Fijalkowska IJ. Dmowski M, et al. Among authors: chabes a. DNA Repair (Amst). 2023 Sep;129:103541. doi: 10.1016/j.dnarep.2023.103541. Epub 2023 Jul 7. DNA Repair (Amst). 2023. PMID: 37481989 Free article.

8

Rapid remodeling of NTP levels enables immediate translational adaptation to energy stress in yeast.

Bexley K, Ristová M, Sharma S, Spanos C, Chabes A, Tollervey D. Bexley K, et al. Among authors: chabes a. Mol Cell. 2025 Oct 2;85(19):3623-3639.e7. doi: 10.1016/j.molcel.2025.08.031. Epub 2025 Sep 19. Mol Cell. 2025. PMID: 40975060 Free PMC article.

9

Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.

Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H. Schmidt TT, et al. Among authors: chabes a. Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4442-E4451. doi: 10.1073/pnas.1618714114. Epub 2017 Apr 17. Proc Natl Acad Sci U S A. 2017. PMID: 28416670 Free PMC article.

10

The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity.

Garbacz MA, Cox PB, Sharma S, Lujan SA, Chabes A, Kunkel TA. Garbacz MA, et al. Among authors: chabes a. Nucleic Acids Res. 2019 May 7;47(8):3986-3995. doi: 10.1093/nar/gkz048. Nucleic Acids Res. 2019. PMID: 30698744 Free PMC article.

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