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A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.
Neuro Oncol. 2017 Jun 1;19(6):774-785. doi: 10.1093/neuonc/now261.
Neuro Oncol. 2017.
PMID: 28082416
Free PMC article.
A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies.
Chadwick EJ, Yang DP, Filbin MG, Mazzola E, Sun Y, Behar O, Pazyra-Murphy MF, Goumnerova L, Ligon KL, Stiles CD, Segal RA.
Chadwick EJ, et al.
J Vis Exp. 2015 Nov 7;(105):e53304. doi: 10.3791/53304.
J Vis Exp. 2015.
PMID: 26575352
Free PMC article.
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A Transposon Screen Identifies Loss of Primary Cilia as a Mechanism of Resistance to SMO Inhibitors.
Zhao X, Pak E, Ornell KJ, Pazyra-Murphy MF, MacKenzie EL, Chadwick EJ, Ponomaryov T, Kelleher JF, Segal RA.
Zhao X, et al. Among authors: chadwick ej.
Cancer Discov. 2017 Dec;7(12):1436-1449. doi: 10.1158/2159-8290.CD-17-0281. Epub 2017 Sep 18.
Cancer Discov. 2017.
PMID: 28923910
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