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Year Number of Results
2006 1
2007 1
2008 1
2009 1
2010 1
2013 1
2014 3
2015 1
2016 3
2017 1
2018 3
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Page 1
Rhodium-Catalyzed Allylic Addition as an Atom-Efficient Approach in Total Synthesis.
Panahi F, Bauer F, Breit B. Panahi F, et al. Acc Chem Res. 2023 Dec 19;56(24):3676-3693. doi: 10.1021/acs.accounts.3c00322. Epub 2023 Dec 8. Acc Chem Res. 2023. PMID: 38064346
The potential of the addition of nitrogen pronucleophiles to allenes was demonstrated in the total syntheses of Cusparein, Angusterein, Cermicin C, Senepodin G, Homoproline, Pipecolinol, Coniceine, Coniine, Ruxolitinib, Sitagliptin, Abacavir, Glucokinase activators, and Chaeto …
The potential of the addition of nitrogen pronucleophiles to allenes was demonstrated in the total syntheses of Cusparein, Angusterein, Cerm …
Homeobox transcription factor HbxA influences expression of over one thousand genes in the model fungus Aspergillus nidulans.
Pandit SS, Zheng J, Yin Y, Lorber S, Puel O, Dhingra S, Espeso EA, Calvo AM. Pandit SS, et al. PLoS One. 2023 Jul 21;18(7):e0286271. doi: 10.1371/journal.pone.0286271. eCollection 2023. PLoS One. 2023. PMID: 37478074 Free PMC article.
For instance, in the opportunistic human pathogen Aspergillus fumigatus, hbxA is involved in conidial production and germination, as well as virulence and secondary metabolism, including production of fumigaclavines, fumiquinazolines, and chaetominine. In the agriculturall …
For instance, in the opportunistic human pathogen Aspergillus fumigatus, hbxA is involved in conidial production and germination, as well as …
Anti-inflammatory alkaloids from the cold-seep-derived fungus Talaromyces helicus SCSIO41311.
Cong M, Zhang Y, Feng X, Pang X, Liu Y, Zhang X, Yang Z, Wang J. Cong M, et al. 3 Biotech. 2022 Aug;12(8):161. doi: 10.1007/s13205-022-03237-9. Epub 2022 Jul 8. 3 Biotech. 2022. PMID: 35818470 Free PMC article.
One new natural alkaloid, chaetominine B (1), together with twenty known compounds was isolated from the South China Sea cold-seep-derived fungus Talaromyces helicus SCSIO41311. ...
One new natural alkaloid, chaetominine B (1), together with twenty known compounds was isolated from the South China Sea cold-seep-de …
Induced effect of Ca(2+) and Al(3+) on chaetominine synthesis by Aspergillus fumigatus CY018 under submerged fermentation.
Liu C, Chen T, Chen J, Zhou Y, Deng L, Feng G, Gao J, Liang H. Liu C, et al. Biotechnol Appl Biochem. 2022 Dec;69(6):2733-2744. doi: 10.1002/bab.2318. Epub 2022 Mar 7. Biotechnol Appl Biochem. 2022. PMID: 34994979
Chaetominine (CHA), an alkaloid with a biological activity obtained from Aspergillus fumigatus CY018, has strong anticancer activity against the human leukemia cells. ...
Chaetominine (CHA), an alkaloid with a biological activity obtained from Aspergillus fumigatus CY018, has strong anticancer activity …
Antitubercular metabolites from the marine-derived fungus strain Aspergillus fumigatus MF029.
Song Z, Liu Y, Gao J, Hu J, He H, Dai S, Wang L, Dai H, Zhang L, Song F. Song Z, et al. Nat Prod Res. 2021 Aug;35(16):2647-2654. doi: 10.1080/14786419.2019.1660331. Epub 2019 Sep 6. Nat Prod Res. 2021. PMID: 34414849
Further chemical investigation resulted in the identification of two new compounds, chaetominine A (1) and sphingofungin I (2), together with four known compounds, emodin (3), chaetominine (4), sphingofungin D (5) and trypacidin (6). ...
Further chemical investigation resulted in the identification of two new compounds, chaetominine A (1) and sphingofungin I (2), toget …
Alkaloids from endophytic fungus Aspergillus fumigatus HQD24 isolated from the Chinese mangrove plant Rhizophora mucronata.
Zou R, Wei C, Zhang X, Zhou D, Xu J. Zou R, et al. Nat Prod Res. 2022 Oct;36(19):5069-5073. doi: 10.1080/14786419.2021.1916017. Epub 2021 Jun 28. Nat Prod Res. 2022. PMID: 34180322
Chemical investigation of endophytic fungus Aspergillus fumigatus HQD24, isolated from the flower of Rhizophora mucronata led to the isolation of eight alkaloids, including pyripyropene A (1), 1,11-dideacetyl-pyripyropene A (2), pyripyropene E (3), chaetominine (4), trypto …
Chemical investigation of endophytic fungus Aspergillus fumigatus HQD24, isolated from the flower of Rhizophora mucronata led to the isolati …
The Transcriptional Regulator HbxA Governs Development, Secondary Metabolism, and Virulence in Aspergillus fumigatus.
Satterlee T, Nepal B, Lorber S, Puel O, Calvo AM. Satterlee T, et al. Appl Environ Microbiol. 2020 Jan 21;86(3):e01779-19. doi: 10.1128/AEM.01779-19. Print 2020 Jan 21. Appl Environ Microbiol. 2020. PMID: 31757831 Free PMC article.
Furthermore, we showed that in A. fumigatus, the loss of hbxA decreased the expression of the brlA central regulatory pathway involved in asexual development, as well as the expression of the "fluffy" genes flbB, flbD, and fluG HbxA was also found to regulate secondary metabolism …
Furthermore, we showed that in A. fumigatus, the loss of hbxA decreased the expression of the brlA central regulatory pathway involved in as …
Rapid Generation of Molecular Complexity by Chemical Synthesis: Highly Efficient Total Synthesis of Hexacyclic Alkaloid (-)-Chaetominine and Its Biosynthetic Implications.
Geng H, Huang PQ. Geng H, et al. Chem Rec. 2019 Feb;19(2-3):523-533. doi: 10.1002/tcr.201800079. Epub 2018 Sep 4. Chem Rec. 2019. PMID: 30252197 Review.
In this account, we demonstrate, through the shortest and also the most efficient asymmetric total syntheses of the hexacyclic alkaloid (-)-chaetominine to date, that on the basis of biogenetic thinking, one can develop quite efficient bio-inspired total synthesis, which i …
In this account, we demonstrate, through the shortest and also the most efficient asymmetric total syntheses of the hexacyclic alkaloid (-)- …
25 results